Cancer-related genes, Transcription factors
Intracellular
Cell type enhanced (Excitatory neurons)
Low immune cell specificity
Low cell line specificity
Component of the DRTF1/E2F transcription factor complex. Binds cooperatively with TFDP1/Dp-1 to E2F sites. Interacts with retinoblastoma protein RB1 and related proteins (such as RBL1) that inhibit the E2F transactivation domain. Binds EAPP.
Activator, DNA-binding
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For Research Use Only. Not For Clinical Use.