Intracellular, Secreted (different isoforms)
Cell type enhanced (Proximal enterocytes, Granulosa cells, Paneth cells)
Low immune cell specificity
Cell line enhanced (BJ hTERT+ SV40 Large T+, BJ hTERT+ SV40 Large T+ RasG12V, GAMG)
Homodimer (PubMed:8288566, PubMed:10950963). Also interacts with BATF (PubMed:8954125). Interacts with TRIM21 (PubMed:26342464). Interacts with NMI; the interaction is direct and is facilitated by TRIM21 (PubMed:10779520, PubMed:10950963, PubMed:26342464).
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For Research Use Only. Not For Clinical Use.