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LTB4R
Receptor for extracellular ATP > UTP and ADP. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. May be the cardiac P2Y receptor involved in the regulation of cardiac muscle contraction through modulation of L-type calcium currents. Is a receptor for leukotriene B4, a potent chemoattractant involved in inflammation and immune response
Protein class
G-protein coupled receptors, Transporters
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Suprabasal keratinocytes, Kupffer cells, Macrophages)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (HaCaT, Karpas-707)
Molecular function
G-protein coupled receptor, Receptor, Transducer
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC
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- Species Reactivity: Human
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: FC
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For Research Use Only. Not For Clinical Use.