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PENK
Met- and Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. PENK(114-133) and PENK(237-258) increase glutamate release in the striatum. PENK(114-133) decreases GABA concentration in the striatum
Protein class
Plasma proteins, Transporters
Predicted location
Secreted
Single cell type specificity
Cell type enhanced (Leydig cells, Basal respiratory cells, Spermatocytes, Peritubular cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (ASC diff, ASC TERT1, BJ, THP-1)
Molecular function
Endorphin, Neuropeptide, Opioid peptide
More Types Infomation
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- Species Reactivity: Human
- Application: IHC-Fr
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IF, IHC, IP
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For Research Use Only. Not For Clinical Use.