Enzymes
Membrane
Cell type enhanced (Extravillous trophoblasts)
Low immune cell specificity
Low cell line specificity
Interacts with INCA1 (PubMed:21750715). Interacts with TMEM43, ENDOD1, TMEM33 and TMED1 to form a complex capable of modulating innate immune signaling through the cGAS-STING pathway (PubMed:32614325). Interacts with UBE2J1; this interaction is important for SQSTM1 ubiquitination (PubMed:33472082).
Transferase
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For Research Use Only. Not For Clinical Use.