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SEC14L2

This gene encodes a cytosolic protein which belongs to a family of lipid-binding proteins including Sec14p, alpha-tocopherol transfer protein, and cellular retinol-binding protein. The encoded protein stimulates squalene monooxygenase which is a downstream enzyme in the cholesterol biosynthetic pathway. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Hepatocytes, Pancreatic endocrine cells, Muller glia cells, Rod photoreceptor cells, Proximal enterocytes)

Immune cell specificity

Immune cell enhanced (naive CD4 T-cell, naive CD8 T-cell)

Cell line specificity

Cell line enhanced (HBEC3-KT, hTCEpi, hTERT-RPE1)

Interaction

Monomer.

Molecular function

Activator

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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