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SPINT1
The protein encoded by this gene is a member of the Kunitz family of serine protease inhibitors. The protein is a potent inhibitor specific for HGF activator and is thought to be involved in the regulation of the proteolytic activation of HGF in injured tissues. Alternative splicing results in multiple variants encoding different isoforms.
Protein class
Cancer-related genes, Plasma proteins
Predicted location
Intracellular, Membrane, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Syncytiotrophoblasts, Cytotrophoblasts, Proximal enterocytes, Distal enterocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (BEWO, HaCaT, hTCEpi, RT4, SK-BR-3, T-47d)
Interaction
Interacts with HGFAC.
Molecular function
Protease inhibitor, Serine protease inhibitor
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, IHC
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For Research Use Only. Not For Clinical Use.