CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins
Intracellular, Membrane (different isoforms)
Group enriched (T-cells, dendritic cells)
Group enriched (naive CD8 T-cell, gdT-cell, T-reg, memory CD8 T-cell, naive CD4 T-cell, memory CD4 T-cell, MAIT T-cell)
Group enriched (JURKAT, MOLT-4)
The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta.
Receptor
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For Research Use Only. Not For Clinical Use.