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EPHX2
This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.
Protein class
Enzymes, Metabolic proteins, Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Proximal tubular cells, Distal tubular cells, Hepatocytes)
Immune cell specificity
Group enriched (naive CD4 T-cell, naive CD8 T-cell, memory CD4 T-cell, T-reg)
Cell line specificity
Cell line enhanced (JURKAT, K-562, OE19)
Interaction
Homodimer.
Molecular function
Hydrolase, Multifunctional enzyme
More Types Infomation
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC
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- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB
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For Research Use Only. Not For Clinical Use.