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MTAP
This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown. [provided by RefSeq, Jul 2008]
Protein class
Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Homotrimer.
Molecular function
Glycosyltransferase, Transferase
More Types Infomation
- APC-B*41:04/Human MTAP (HEEAVSVDRVL) MHC Tetramer (MHC-LC1584)
-
- Class: Class I
- Antigen: MTAP
- Antigen Species: Human
- Peptide: HEEAVSVDRVL
- Conjugate: APC
- PE-B*41:04/Human MTAP (HEEAVSVDRVL) MHC Tetramer (MHC-LC1583)
-
- Class: Class I
- Antigen: MTAP
- Antigen Species: Human
- Peptide: HEEAVSVDRVL
- Conjugate: PE
- BV421-B*41:04/Human MTAP (HEEAVSVDRVL) MHC Tetramer (MHC-LC1585)
-
- Class: Class I
- Antigen: MTAP
- Antigen Species: Human
- Peptide: HEEAVSVDRVL
- Conjugate: BV421
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IP
- Recombinant Mouse Anti-Human MTAP Antibody (MOB-0930MZ)
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: ICC/IF
-
- Type: Rabbit IgG
- Application: IA
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For Research Use Only. Not For Clinical Use.