PE-B*41:04/Human MTAP (HEEAVSVDRVL) MHC Tetramer
CAT#: MHC-LC1583
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of MTAP-derived peptide of HEEAVSVDRVL covering 227-237 and B*41:04 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to nucleoplasm & cytosol.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/46915/1916_C10_25_cr5c99f3ba8408a_selected.jpg
Normal Tissue
Figure 2 IHC staining of human endometrium
Immunohistochemical staining of human endometrium shows moderate nuclear and cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/80036/170588_B_5_3_selected.jpg
Normal Tissue
Figure 3 IHC staining of human esophagus
Immunohistochemical staining of human esophagus shows strong nuclear and cytoplasmic positivity in squamous epithelial cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/80037/170596_B_6_1_selected.jpg
Normal Tissue
Figure 4 Cerebral cortex
Endothelial cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/80037/170596_B_7_5.jpg
Normal Tissue
Figure 5 Colon
Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/80037/170596_A_9_3.jpg
Normal Tissue
Figure 6 Kidney
Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous nuclear
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/80037/170596_A_9_5.jpg
Normal Tissue
Figure 7 Lymph node
Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/80037/170596_A_7_8.jpg
RNA Expression
Figure 8 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000099810-MTAP
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Specifications
- Allele
- B*41:04
- Class
- Class I
- MHC Species
- Human
- Antigen
- MTAP
- Antigen Species
- Human
- Peptide
- HEEAVSVDRVL
- Range
- 227-237
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.
- Alternative Names
- MTAP; methylthioadenosine phosphorylase; BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86fus; HEL-249
- Gene ID
- 4507
- UniProt ID
- Q13126
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COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0930MZ | Recombinant Mouse Anti-Human MTAP Antibody | ICC, IF | Mouse antibody |
| VS3-FY966 | Recombinant Rabbit Anti-MTAP Antibody (VS3-FY966) | IA | Rabbit IgG |
| VS3-FY2040 | Rabbit Anti-MTAP Recombinant Antibody (clone R07-5A0) | WB | Rabbit IgG |
| VS3-FY2810 | Rabbit Anti-MTAP Recombinant Antibody (VS3-FY2810) | WB, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-LC1584 | APC-B*41:04/Human MTAP (HEEAVSVDRVL) MHC Tetramer | FCM | |
| MHC-LC1585 | BV421-B*41:04/Human MTAP (HEEAVSVDRVL) MHC Tetramer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-2314 | Hi-Affi™ Recombinant Rabbit Anti-MTAP Monoclonal Antibody (DS2314AB) | WB, IP | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY4557 | Anti-MTAP Immunohistochemistry Kit | IHC |
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