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MYOG
Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle. [provided by RefSeq, Jul 2008]
Protein class
Cancer-related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Skeletal myocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (HSkMC, RH-30)
Interaction
Homodimer and heterodimer with E12; heterodimerization enhances MYOG DNA-binding and transcriptional activities. Interacts with SMARCA4/BRG1/BAF190A. Interacts (via C-terminal region) with SSRP1 and SUPT16H; the interaction is indicative of an interaction with the FACT complex (By similarity). Interacts with CSRP3.
Molecular function
Activator, Developmental protein, DNA-binding
More Types Infomation
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: IHC
- Mouse Anti-MYOG Recombinant Antibody (MOB-0134F) (MOB-0134F)
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- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
- Mouse Anti-MYOG Recombinant Antibody (MOB-0133F) (MOB-0133F)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: IHC-P, IF
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC, IF, IHC
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, FC
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: IHC-P
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- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IHC-P
-
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: IHC-P
-
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: ELISA, GS, IHC-P, IF, IP, WB
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For Research Use Only. Not For Clinical Use.