Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins
Intracellular
Cell type enhanced (Late spermatids, Early spermatids)
Low immune cell specificity
Low cell line specificity
Homodimer. Interacts with RHOB, RHOC, MYLC2B and PTEN. Interacts with ITGB1BP1 (via N-terminus and PTB domain) (By similarity). Interacts with RHOA (activated by GTP), CHORDC1, DAPK3, GEM, JIP3, RHOE, PPP1R12A, PFN1, LIMK1, LIMK2 and TSG101. Interacts with FHOD1 in a Src-dependent manner. Interacts with SHROOM3 (PubMed:22493320).
Kinase, Serine/threonine-protein kinase, Transferase
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For Research Use Only. Not For Clinical Use.