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SYP
This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability.
Protein class
Disease related genes, Human disease related genes, Potential drug targets, Transporters
Predicted location
Membrane
Single cell type specificity
Group enriched (Rod photoreceptor cells, Cone photoreceptor cells, Bipolar cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (K-562, SCLC-21H, SH-SY5Y)
Interaction
Homohexamer or homotetramer. Interacts with SRCIN1 (PubMed:18662323). Interacts with VAMP2; the interaction is inhibit by interaction of VAPM2 with SEPT8 (By similarity).
More Types Infomation
- Rabbit Anti-SYP Polyclonal Antibody (MRO-2206-CN) (MRO-2206-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Species Reactivity: Mouse, Rat, Human
- Type: IgG
- Application: WB, IF, ICC, FC
- Mouse Anti-SYP Recombinant Antibody (clone SP15) (FAMAB-1544CQ)
-
- Species Reactivity: Cat, Hamster, Pig, Human, Rat
- Type: Mouse IgM
- Application: WB, ELISA, IHC
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC
- Recombinant Mouse Anti-SYP Monoclonal Antibody (A1-7) (MRO-1461-CN)
-
- Species Reactivity: Mouse, Rat
- Type: Mouse IgG1
- Application: WB, IF, IHC, FC
-
- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
- Mouse Anti-SYP Recombinant Antibody (clone 23G4) (MOB-1588z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgM, κ
- Application: WB, IP
- Mouse Anti-SYP Antibody (clone SP15), mRNA (FAMAB-1544CQ-mRNA)
-
- Species Reactivity: Cat, Hamster, Pig, Human, Rat
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: IHC-FoFr, IHC-P, WB
-
- Type: Mouse IgM
- Application: WB
- Human Anti-SYP Antibody, mRNA (TAB-588CL-mRNA)
-
- Species Reactivity: Human
- Anti-Human Synaptophysin Recombinant Antibody scFv Fragment (C1-3) (TAB-494CT-S(P))
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FC
-
- Derivation: Human
- Species Reactivity: Human
- Type: ADCC enhanced antibody
- Anti-Human SYP Recombinant Antibody (TAB-588CL)
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- Derivation: Human
- Species Reactivity: Human
- Type: Antibody
- Mouse Anti-SYP Recombinant Antibody (clone 7H12) (VS3-QX1079)
-
- Derivation: Mouse
- Species Reactivity: Human, Rat
- Type: Mouse IgG1
- Application: WB, IHC, ICC, FC, ELISA
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1, κ
- Application: WB
-
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: IHC-P
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IHC-P
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Human antibody
- Application: ELISA, FC
- Recombinant Rabbit Anti-SYP Antibody (clone R06-2A2) (VS3-FY1421)
-
- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IHC-Fr, IHC-P, ICC, IF
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For Research Use Only. Not For Clinical Use.