Rat Anti-CD276 Recombinant Antibody (clone MJ18) (CAT#: NEUT-333CQ)
This antibody is a rat monoclonal antibody that binds specifically to mouse CD276 (B7-H3), and it can neutralize the bioactivity of mouse CD276 (B7-H3).
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17139/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17139/if_selected.jpg
Figure 2 Placenta.
(High expression in placenta)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17826/40943_A_1_7_val_selected.jpg
(High expression in placenta)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/17826/40943_A_1_7_val_selected.jpg
Figure 3 Testis
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_A_5_6.jpg
(Cells in seminiferous ducts Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_A_5_6.jpg
Figure 4 Cerebral cortex
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_B_7_5.jpg
(Neuropil Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_B_7_5.jpg
Figure 5 Colon
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_A_9_3.jpg
(Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_A_9_3.jpg
Figure 6 Liver
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_A_7_4.jpg
(Cholangiocytes Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Hepatocytes Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/9285/25731_A_7_4.jpg
Figure 7 RNA cell line category: Cell line enhanced (HaCaT, U-2197)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000103855-CD276
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000103855-CD276
Specifications
- Host Species
- Rat
- Type
- Rat IgG1
- Specificity
- Recognizes Mouse CD276 (B7-H3)
- Species Reactivity
- Mouse
- Clone
- MJ18
- Applications
- Block, FC
- Conjugate
- Unconjugated
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Cd276; CD276 antigen; B7h3; B7RP-2; AU016588; 6030411F23Rik
- Gene ID
- 102657
- UniProt ID
- Q8VE98
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD276"
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-117CL | Anti-Human CD276 Recombinant Antibody (MGA271) | ADCC, FuncS | Antibody |
| TAB-424CQ | Anti-Human CD276 Recombinant Antibody (Enoblituzumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0549 | Hi-Affi™ Rabbit Anti-CD276 Recombinant Antibody (clone DS549AB) | WB, IP, FC | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0241-CN | Human Anti-CD276 Recombinant Antibody (HPAB-0241-CN) | ELISA, FC, IP | Chimeric (mouse/human) IgG1, κ |
| HPAB-0048LY | Mouse Anti-CD276 Recombinant Antibody (HPAB-0048LY) | FuncS, ELISA, FC, IHC | Mouse IgG |
| HPAB-0049LY | Human Anti-CD276 Recombinant Antibody (HPAB-0049LY) | FuncS, ELISA, FC, IHC | Humanized IgG |
| FN-232CQ | Rat Anti-CD276 Recombinant Antibody (VMC215) | FC, FuncS, IF | Rat IgG2a |
| FN-239CQ | Rat Anti-CD276 Recombinant Antibody (clone MIH35) | FC, FuncS | Rat IgG2a, κ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0048LY-S(P) | Mouse Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-0048LY-S(P)) | FuncS, ELISA, FC, IHC | Mouse scFv |
| HPAB-0049LY-S(P) | Human Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-0049LY-S(P)) | FuncS, ELISA, FC, IHC | Human scFv |
| HPAB-M0422-YC-S(P) | Mouse Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-M0422-YC-S(P)) | Cyt, FuncS | Mouse scFv |
| HPAB-M0423-YC-S(P) | Mouse Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-M0423-YC-S(P)) | Cyt, FuncS | Mouse scFv |
| HPAB-M0424-YC-S(P) | Human Anti-CD276 Recombinant Antibody; scFv Fragment (HPAB-M0424-YC-S(P)) | Cyt, FuncS, IHC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-M0422-YC-F(E) | Mouse Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-M0422-YC-F(E)) | Cyt, FuncS | Mouse Fab |
| HPAB-M0423-YC-F(E) | Mouse Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-M0423-YC-F(E)) | Cyt, FuncS | Mouse Fab |
| HPAB-M0424-YC-F(E) | Human Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-M0424-YC-F(E)) | Cyt, FuncS, IHC | Humanized Fab |
| HPAB-M0425-YC-F(E) | Mouse Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-M0425-YC-F(E)) | Cyt, FuncS | Mouse Fab |
| HPAB-M0426-YC-F(E) | Human Anti-CD276 Recombinant Antibody; Fab Fragment (HPAB-M0426-YC-F(E)) | Cyt, FuncS, IHC | Humanized Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-424CQ | Afuco™ Anti-CD276 ADCC Recombinant Antibody (Enoblituzumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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