Antibody S5B4 is a novel human antibody that specifically binds to human IFNAR1, which can inhibit the type I interferon-mediated cell signaling pathway.
Figure 1 IFNAR blockade during cART reduces cART-resistant HIV-1 reservoirs.
Hu-mice infected with HIV-1 were treated with cART from 4 to 12 wpi. From 7 to 10 wpi, the cART-treated mice were injected with α-IFNAR1 antibody or isotype control mIgG2a antibody.
Cheng, L., Ma, J., Li, J., Li, D., Li, G., Li, F., ... & Tsao, L. C. (2017). Blocking type I interferon signaling enhances T cell recovery and reduces HIV-1 reservoirs. The Journal of clinical investigation, 127(1), 269-279.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1305z-S(P) | Recombinant Anti-Human IFNAR1 Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
PSBL-228 | Human Anti-IFNAR1 Recombinant Antibody (clone MEDI546); scFv Fragment | WB, ELISA, FuncS | Human scFv |
HPAB-M0362-YC-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone H15D10+L8C3); scFv Fragment | ELISA | Human scFv |
HPAB-M0363-YC-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone H19B7+L8C3); scFv Fragment | ELISA | Human scFv |
HPAB-M0364-YC-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone H15D10+L16C11); scFv Fragment | ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-130CT | Anti-Human IFNAR-1 Recombinant Antibody (64G12) | WB, IF, FuncS | |
TAB-130CT-S(P) | Anti-Human IFNAR-1 Recombinant Antibody scFv Fragment (64G12) | ELISA, FC | |
TAB-130CT-F(E) | Anti-Human IFNAR-1 Recombinant Antibody Fab Fragment (64G12) | ELISA, FC |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-131CT | Anti-Human IFNAR-1 Recombinant Antibody (CPI-1697) | ELISA, FC | Humanized antibody |
TAB-131CT-S(P) | Anti-Human IFNAR-1 Recombinant Antibody scFv Fragment (CPI-1697) | ELISA, FC | Humanized antibody |
TAB-131CT-F(E) | Anti-Human IFNAR-1 Recombinant Antibody Fab Fragment (CPI-1697) | ELISA, FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-976CQ | Mouse Anti-Ifnar1 Recombinant Antibody (clone MAR1-5A3) | FC, Neut, IP, WB, B | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1740 | Rabbit Anti-IFNAR1 Recombinant Antibody (clone DS1740AB) | WB, FC, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0203CQ | Human Anti-IFNAR1 Recombinant Antibody (clone H3K1) | ELISA, FC, Inhib | Humanized IgG1 |
HPAB-0204CQ | Human Anti-IFNAR1 Recombinant Antibody (HPAB-0204CQ) | ELISA, WB, FC, Inhib, FuncS | Human IgG1 |
HPAB-0205CQ | Human Anti-IFNAR1 Recombinant Antibody (HPAB-0205CQ) | ELISA, WB, FC, Inhib | Human IgG1 |
HPAB-0206CQ | Human Anti-IFNAR1 Recombinant Antibody (HPAB-0206CQ) | ELISA, WB, FC, Inhib | Human IgG1 |
HPAB-0207CQ | Human Anti-IFNAR1 Recombinant Antibody (HPAB-0207CQ) | ELISA, WB, FC, Inhib, FuncS | Human IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0203CQ-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone H3K1); Fab Fragment | ELISA, FC, Inhib | Humanized Fab |
HPAB-M0362-YC-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone H15D10+L8C3); Fab Fragment | ELISA | Human Fab |
HPAB-M0363-YC-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone H19B7+L8C3); Fab Fragment | ELISA | Human Fab |
HPAB-M0364-YC-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone H15D10+L16C11); Fab Fragment | ELISA | Human Fab |
HPAB-M0365-YC-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone H19B7+L16C11); Fab Fragment | ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-722 | Afuco™ Anti-IFNAR ADCC Recombinant Antibody (Anifrolumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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