Afuco™ Anti-IFNAR ADCC Recombinant Antibody (Anifrolumab), ADCC Enhanced (CAT#: AFC-TAB-722)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant human monoclonal antibody expressed in CHO binding to human interferon α/β receptor. Anifrolumab is a monoclonal antibody designed for the treatment of systemic lupus erythematosus.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_B_9_5.jpg
(Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_B_9_5.jpg
Figure 2 Testis
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_4_6.jpg
(Cells in seminiferous ducts
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Leydig cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_4_6.jpg
Figure 3 Lymph node
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_9_8.jpg
(Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/29226/75714_A_9_8.jpg
Figure 4 RNA cell line category: Cell line enhanced (Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1
Figure 4 RNA cell line category: Cell line enhanced (Karpas-707)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142166-IFNAR1
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Clone
- Anifrolumab
- Applications
- FuncS, IF, Neut, ELISA, FC, IP
- Conjugate
- Unconjugated
- Generic Name
- Anifrolumab
- Related Disease
- Diffuse scleroderma
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Anifrolumab; 1326232-46-5; MEDI-546; interferon-α/β receptor; IFNAR
Related Resources
Please refer to Anifrolumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Anifrolumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "anifrolumab"
Anti-IFNAR Recombinant Antibody (Anifrolumab)Recombinant human monoclonal antibody expressed in CHO binding to human interferon α/β receptor. Anifrolumab is a monoclonal antibody designed for the treatment of systemic lupus erythematosus.
See other products for "IFNAR1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1305z | Mouse Anti-IFNAR1 Recombinant Antibody (MOB-1305z) | ELISA, WB, IP, IF, IHC, FC | Mouse IgG1, κ |
| PABL-228 | Human Anti-IFNAR1 Recombinant Antibody (clone MEDI546) | WB, ELISA, FuncS | Human IgG |
| HPAB-0158-CN | Human Anti-IFNAR1 Recombinant Antibody (clone S3A5) | FC | Human IgG |
| HPAB-0159-CN | Human Anti-IFNAR1 Recombinant Antibody (clone S5B4) | FC | Human IgG |
| HPAB-0160-CN | Human Anti-IFNAR1 Recombinant Antibody (clone AmS3A5-1) | ELISA | Human IgG1, κ |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1305z-S(P) | Recombinant Anti-Human IFNAR1 Antibody scFv Fragment | RIA, ELISA, FuncS | scFv |
| HPAB-0158-CN-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone S3A5); scFv Fragment | ELISA | Human scFv |
| HPAB-0159-CN-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone S5B4); scFv Fragment | ELISA | Human scFv |
| HPAB-0160-CN-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone AmS3A5-1); scFv Fragment | ELISA | Human scFv |
| HPAB-0161-CN-S(P) | Human Anti-IFNAR1 Recombinant Antibody (clone AmS3A5-2); scFv Fragment | ELISA | Human scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-130CT | Anti-Human IFNAR-1 Recombinant Antibody (64G12) | WB, IF, FuncS | |
| TAB-130CT-S(P) | Anti-Human IFNAR-1 Recombinant Antibody scFv Fragment (64G12) | ELISA, FC | |
| TAB-130CT-F(E) | Anti-Human IFNAR-1 Recombinant Antibody Fab Fragment (64G12) | ELISA, FC |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-131CT | Anti-Human IFNAR-1 Recombinant Antibody (CPI-1697) | ELISA, FC | Humanized antibody |
| TAB-131CT-S(P) | Anti-Human IFNAR-1 Recombinant Antibody scFv Fragment (CPI-1697) | ELISA, FC | Humanized antibody |
| TAB-131CT-F(E) | Anti-Human IFNAR-1 Recombinant Antibody Fab Fragment (CPI-1697) | ELISA, FC | Humanized antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-976CQ | Mouse Anti-Ifnar1 Recombinant Antibody (clone MAR1-5A3) | FC, Neut, IP, WB, B | Mouse IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1740 | Rabbit Anti-IFNAR1 Recombinant Antibody (clone DS1740AB) | WB, FC, IP | Rabbit IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0203CQ-F(E) | Human Anti-IFNAR1 Recombinant Antibody (clone H3K1); Fab Fragment | ELISA, FC, Inhib | Humanized Fab |
| HPAB-0204CQ-F(E) | Human Anti-IFNAR1 Recombinant Antibody; Fab Fragment (HPAB-0204CQ-F(E)) | ELISA, WB, FC, Inhib | Human Fab |
| HPAB-0205CQ-F(E) | Human Anti-IFNAR1 Recombinant Antibody; Fab Fragment (HPAB-0205CQ-F(E)) | ELISA, WB, FC, Inhib | Human Fab |
| HPAB-0206CQ-F(E) | Human Anti-IFNAR1 Recombinant Antibody; Fab Fragment (HPAB-0206CQ-F(E)) | ELISA, WB, FC, Inhib | Human Fab |
| HPAB-0207CQ-F(E) | Human Anti-IFNAR1 Recombinant Antibody; Fab Fragment (HPAB-0207CQ-F(E)) | ELISA, WB, FC, Inhib | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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