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COPS8

COPS8 (COP9 Signalosome Subunit 8) is a Protein Coding gene. Diseases associated with COPS8 include Xeroderma Pigmentosum, Complementation Group E and Familial Hypertension. Among its related pathways are Transcription-Coupled Nucleotide Excision Repair (TC-NER) and Vesicle-mediated transport.
Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (hTERT-HME1, U-138 MG)

Interaction

Component of the CSN complex, composed of COPS1/GPS1, COPS2, COPS3, COPS4, COPS5, COPS6, COPS7 (COPS7A or COPS7B), COPS8 and COPS9 isoform 1 (PubMed:11337588, PubMed:18850735, PubMed:26456823). In the complex, it probably interacts directly with COPS3, COPS4 and COPS7 (COPS7A or COPS7B) (PubMed:18850735).

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For Research Use Only. Not For Clinical Use.

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