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MELK
MELK (Maternal Embryonic Leucine Zipper Kinase) is a Protein Coding gene. Diseases associated with MELK include Uterine Corpus Endometrial Carcinoma. Among its related pathways are Neuroscience. Gene Ontology (GO) annotations related to this gene include calcium ion binding and protein kinase activity. An important paralog of this gene is PRKAA2.
Protein class
Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Extravillous trophoblasts, Spermatocytes, Spermatogonia, Cytotrophoblasts, Erythroid cells)
Immune cell specificity
Immune cell enriched (T-reg)
Cell line specificity
Low cell line specificity
Interaction
Monomer. Interacts with ZNF622 and PPP1R8.
Molecular function
Kinase, Serine/threonine-protein kinase, Transferase
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB
- Mouse Anti-MELK Recombinant Antibody (clone 2G2) (VS3-XY1060)
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- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, IHC, FC, ICC
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For Research Use Only. Not For Clinical Use.