Enzymes, Metabolic proteins, Plasma proteins
Membrane, Secreted (different isoforms)
Cell type enriched (Oligodendrocyte precursor cells)
Not detected in immune cells
Group enriched (AF22, NTERA-2, WM-115)
The carbonic-anhydrase like domain interacts with CNTN1 (contactin) (PubMed:20133774). Interacts with PTN (PubMed:16814777). Interaction with PTN promotes formation of homooligomers; oligomerization impairs phosphatase activity (By similarity). Interacts (via chondroitin sulfate chains) with MDK (via C-terminal); this interaction is inhibited by PTN; this interaction promotes neuronal migration (By similarity).
Hydrolase, Protein phosphatase
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For Research Use Only. Not For Clinical Use.