Loading...
RELB
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in cytosol and nucleoplasm. Part of chromatin; nucleus; and transcription repressor complex. Colocalizes with centrosome. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma.
Protein class
Cancer-related genes, Disease related genes, Plasma proteins, Transcription factors
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Prostatic glandular cells, monocytes, Plasma cells, Basal prostatic cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (Daudi, HDLM-2, U-698)
Interaction
Component of the NF-kappa-B RelB-p50 complex. Component of the NF-kappa-B RelB-p52 complex. Self-associates; the interaction seems to be transient and may prevent degradation allowing for heterodimer formation with p50 or p52. Interacts with NFKB1/p50, NFKB2/p52 and NFKB2/p100. Interacts with NFKBID. Interacts with ARNTL/BMAL1 and the interaction is enhanced in the presence of CLOCK (By similarity).
Molecular function
Activator, DNA-binding, Repressor
More Types Infomation
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: ICC/IF, IHC-P, IP, WB
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
- Mouse Anti-RELB Recombinant Antibody (VS3-WK841) (VS3-WK841)
-
- Derivation: Mouse
- Species Reactivity: Human, Mouse
- Type: Mouse IgG
- Application: WB
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-P, ICC, IF, IP, FC
-
- Derivation: Rabbit
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, IP
- Mouse Anti-RELB Recombinant Antibody (clone 2E4B1) (VS3-XY1367)
-
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ICC, FC
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.