Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins
Intracellular, Secreted (different isoforms)
Cell type enhanced (Hepatic stellate cells, Fibroblasts, Langerhans cells, Smooth muscle cells, Leydig cells, Macrophages, Peritubular cells)
Low immune cell specificity
Cell line enhanced (ASC diff, ASC TERT1, fHDF/TERT166, HSkMC)
Interacts with MMP1, MMP3, MMP10 and MMP13, but has only very low affinity for MMP14. Interacts with CD63; identified in a complex with CD63 and ITGB1.
Growth factor, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor
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For Research Use Only. Not For Clinical Use.