Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins
Intracellular
Cell type enhanced (Extravillous trophoblasts)
Immune cell enhanced (neutrophil)
Low cell line specificity
Homodimer; antiparallel. Interacts with MYOZ2, TTID and LPP (PubMed:10369880, PubMed:11114196, PubMed:12615977). Interacts with DDN (PubMed:16464232). Interacts with PSD. Interacts with MICALL2 (By similarity). Interacts with DNM2 and CTTN. Interacts with PDLIM1. Interacts with PDLIM2. Interacts with PDLIM4 (via PDZ domain) (By similarity).
Actin-binding
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For Research Use Only. Not For Clinical Use.