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COL18A1
COL18A1 (Collagen Type XVIII Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL18A1 include Knobloch Syndrome 1 and Knobloch Syndrome. Among its related pathways are Integrin Pathway and ERK Signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding and structural molecule activity. An important paralog of this gene is COL15A1.
Protein class
Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins
Predicted location
Intracellular, Secreted (different isoforms)
Single cell type specificity
Cell type enhanced (Hepatocytes, Smooth muscle cells, Sertoli cells)
Immune cell specificity
Immune cell enhanced (neutrophil)
Cell line specificity
Cell line enhanced (BJ hTERT+, EFO-21, NTERA-2, RPTEC TERT1, TIME)
Interaction
[Non-collagenous domain 1]: Forms homotrimers (PubMed:11257123). Recombinant non-collagenous domain 1 has stronger affinity to NID1, HSPG2 and laminin-1:NID1 complex and lower affinity to FBLN1 and FBLN2 than endostatin (By similarity). [Endostatin]: Monomeric (PubMed:11257123). Interacts with KDR/VEGFR2. Interacts with the ITGA5:ITGB1 complex. Interacts with NID1, HSPG2, laminin-1:NID1 complex, FBLN1 and FBLN2 (By similarity).
More Types Infomation
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, IP, IF, ELISA
- Recombinant Human Anti-COL18A1 Soluble TCR (L14) (C-Cys) (VS-0622-YF3835)
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- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (I1) (C-Cys) (VS-0622-YF3834)
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- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (H19) (C-Cys) (VS-0622-YF3833)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (L14) (KIH) (VS-0622-YF6543)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (I1) (KIH) (VS-0622-YF6542)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (H19) (KIH) (VS-0622-YF6541)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (BG4) (KIH) (VS-0622-YF6540)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (BG4) (C-Cys) (VS-0622-YF3832)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Human Anti-COL18A1 Recombinant Soluble TCR (L14) (scTCR-374ZP-S(P))
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Human Anti-COL18A1 Recombinant Soluble TCR (I1) (scTCR-373ZP-S(P))
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Human Anti-COL18A1 Recombinant Soluble TCR (H19) (scTCR-372ZP-S(P))
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Human Anti-COL18A1 Recombinant Soluble TCR (BG4) (scTCR-371ZP-S(P))
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
-
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA
-
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
- Recombinant Human Anti-COL18A1 Soluble TCR (L14) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1127)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (I1) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1126)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (H19) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1125)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
- Recombinant Human Anti-COL18A1 Soluble TCR (BG4) (ZIP-Fos/ZIP-Jun) (VS-0622-YF1124)
-
- Species Reactivity: Human
- Epitope: VLLGVKLSGV
- MHC: HLA-A2
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For Research Use Only. Not For Clinical Use.