PE-A*02:01/Human OPN4 (TLGTVILLV) MHC Tetramer (CAT#: MHC-LC3044)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human OPN4 of peptide TLGTVILLV covering 72-80 and A*02:01 molecule. The pMHC tetramer recognizes CD8 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Normal Tissue
Figure 1 Kidney
(Cells in glomeruli Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39147/160954_A_7_5.jpg
(Cells in glomeruli Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous Cells in tubules Staining: Not detected Intensity: Weak Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/39147/160954_A_7_5.jpg
Specifications
- Allele
- A*02:01
- Class
- Class I
- MHC Species
- Human
- Antigen
- OPN4
- Antigen Species
- Human
- Peptide
- TLGTVILLV
- Range
- 72-80
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. This gene encodes a photoreceptive opsin protein that is expressed within the ganglion and amacrine cell layers of the retina. In mouse, retinal ganglion cell axons expressing this gene projected to the suprachiasmatic nucleus and other brain nuclei involved in circadian photoentrainment. In mouse, this protein is coupled to a transient receptor potential (TRP) ion channel through a G protein signaling pathway and produces a physiologic light response via membrane depolarization and increased intracellular calcium. The protein functions as a sensory photopigment and may also have photoisomerase activity. Experiments with knockout mice indicate that this gene attenuates, but does not abolish, photoentrainment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Alternative Names
- OPN4; seven transmembrane helix receptor; MOP
- Gene ID
- 94233
- UniProt ID
- Q9UHM6
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
Customer Reviews and Q&As
There are currently no Customer reviews or questions for MHC-LC3044. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.