H-2Db/Lymphocytic choriomeningitis mammarenavirus Nucleoprotein (FQPQNGQFI) MHC Pentamer (CAT#: MHC-YC217)
MHC multimers have a high avidity for CD8 T cells, and can be used in the analysis of individual antigen-specific T cells. This product is a Pentamer of peptide/MHC complex with LCMV-derived peptide of FQPQNGQFI sequence covering 396-404 and H-2Db molecule. The peptide/MHC pentamer provided here is unlabeled or fluorescent labeled such as Biotin, R-PE, APC. And all of them are available in 50, 150 or 500 tests.
Specific Inquiry
Specifications
- Allele
- H-2Db
- Class
- Class I
- Antigen
- Lymphocytic choriomeningitis mammarenavirus Nucleoprotein
- Antigen Species
- LCMV
- Peptide
- FQPQNGQFI
- Range
- 396-404
- Conjugate
- Unlabeled, Biotin, R-PE, APC
- Application
- FCM
Target
- Antigen Introduction
- Encapsidates the genome, protecting it from nucleases. template for viral transcription and replication. The increased presence of protein N in host cell does not seem to trigger the switch from transcription to replication as observed in other negative strain RNA viruses. Through the interaction with host IKBKE, strongly inhibits the phosphorylation and nuclear translocation of host IRF3, a protein involved in interferon activation pathway, leading to the inhibition of interferon-beta and IRF3-dependent promoters activation. Encodes also a functional 3'-5' exoribonuclease that degrades preferentially dsRNA substrates and therby participates in the suppression of interferon induction.
- Alternative Names
- LCMVsSgp2
- Gene ID
- 956592
- UniProt ID
- P09992
Downloads
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Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-2240CQ | Recombinant Mouse Anti-LCMV NP Antibody (M104) | IF, WB, IHC-Fr | Mouse antibody |
MHC Tetramer for Virology
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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