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TMPRSS2

The anti-Pro115 antibodies that bind to Pro115 are used in treating Pro115-expressing cancers such as prostate, colon, lung or pancreas cancers.
Protein class

Cancer-related genes, Enzymes, Transporters

Predicted location

Intracellular, Membrane, Secreted (different isoforms)

Single cell type specificity

Cell type enhanced (Distal enterocytes, Paneth cells, Prostatic glandular cells, Urothelial cells, Proximal enterocytes, Gastric mucus-secreting cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (CACO-2, MCF7, OE19, RT4, SK-BR-3)

Interaction

The catalytically active form interacts with ACE2.

Molecular function

Hydrolase, Protease, Serine protease

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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