Anti-Human TMPRSS2 Recombinant Antibody (CAT#: TAB-620CL)
Recombinant Humanized monoclonal antibody expressed in CHO binding to Human TMPRSS2. The anti-Pro115 antibodiess that bind to Pro115 are used in treating Pro115-expressing cancers such as prostate, colon, lung or pancreas cancers.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line CACO-2
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34493/1239_B5_1_selected.jpg
(Immunofluorescent staining of human cell line CACO-2 shows localization to nucleoplasm & plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/34493/1239_B5_1_selected.jpg
Figure 2 Colon
(Endocrine cells Staining: Low Intensity: Weak Enterocytes Staining: Low Intensity: Weak Quantity: 75%-25% Enterocytes - Microvilli Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35787/133536_A_8_3.jpg
(Endocrine cells Staining: Low Intensity: Weak Enterocytes Staining: Low Intensity: Weak Quantity: 75%-25% Enterocytes - Microvilli Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35787/133536_A_8_3.jpg
Figure 3 Kidney
(Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35787/133536_A_8_5.jpg
(Distal tubules Staining: Medium Intensity: Moderate Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35787/133536_A_8_5.jpg
Figure 4 High expression in prostate
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35787/133536_A_2_5.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/35787/133536_A_2_5.jpg
Figure 5 RNA cell line category: Cell line enhanced (CACO-2, MCF7, OE19, RT4, SK-BR-3)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000184012-TMPRSS2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000184012-TMPRSS2
Specifications
- Derivation
- Humanized
- Type
- Antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >95%, by SDS-PAGE, under reducing conditions
- Storage
- 4 °C, -20°C if preferred
Target
- Alternative Names
- TMPRSS2; transmembrane protease, serine 2; PP9284; PRSS10; transmembrane protease serine 2; epitheliasin; serine protease 10
- Gene ID
- 7113
- UniProt ID
- O15393
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-714CT-F(E) | Mouse Anti-TMPRSS2 Recombinant Antibody; Fab Fragment (TAB-714CT-F(E)) | WB, ELISA, FC | Mouse Fab |
| TAB-715CT-F(E) | Mouse Anti-TMPRSS2 Recombinant Antibody; Fab Fragment (TAB-715CT-F(E)) | WB, ELISA, FC | Mouse Fab |
| TAB-716CT-F(E) | Mouse Anti-TMPRSS2 Recombinant Antibody; Fab Fragment (TAB-716CT-F(E)) | WB, ELISA, FC | Mouse Fab |
| TAB-717CT-F(E) | Mouse Anti-TMPRSS2 Recombinant Antibody; Fab Fragment (TAB-717CT-F(E)) | WB, ELISA, FC | Mouse Fab |
| TAB-718CT-F(E) | Mouse Anti-TMPRSS2 Recombinant Antibody; Fab Fragment (TAB-718CT-F(E)) | WB, ELISA, FC | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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