PE-DQB1*02:01/Human HLA-DQw4 (YQSYGPSGQYTHEFD) MHC Tetramer (CAT#: MHC-LC3285)
This product is a tetramer of biotinylated peptide/MHC complex with streptavidin mainly composed of human HLA-DQw4 of peptide YQSYGPSGQYTHEFD covering 16-30 and DQB1*02:01 molecule. The pMHC tetramer recognizes CD4 T cells, and can be used in the analysis of individual antigen-specific T cells.
Specific Inquiry
Specifications
- Allele
- DQB1*02:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- HLA-DQw4
- Antigen Species
- Human
- Peptide
- YQSYGPSGQYTHEFD
- Range
- 16-30
- Conjugate
- PE
- Application
- FCM
Target
- Antigen Introduction
- HLA-DQ (DQ) is a cell surface receptor protein found on antigen presenting cells. It is an αβ heterodimer of type MHC class II. The α and β chains are encoded by two loci, HLA-DQA1 and HLA-DQB1, that are adjacent to each other on chromosome band 6p21.3. Both α-chain and β-chain vary greatly. A person often produces two α-chain and two β-chain variants and thus 4 isoforms of DQ. The DQ loci are in close genetic linkage to HLA-DR, and less closely linked to HLA-DP, HLA-A, HLA-B and HLA-C.
- Alternative Names
- HLA-DQw4; HLA DQw4 alpha
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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