Monkey Anti-HIV-1 gp120 Recombinant Antibody (clone LV23) (CAT#: MRO-3549CQ)
Recombinant Macaque Antibody to gp120. LV23 showed potent neutralizing activity against the homologous virus (SF162).
Specific Inquiry
Neut
Figure 1 Neutralization curves for eight RhMAbs and human MAb 2909 against HIV-1 pseudotyped with wt SF162 Env.
These curves and neutralization endpoints are representative of multiple assays.
Krachmarov, C.P., Lai, Z.X., Honnen, W.J., Salomon, A., Gorny, M.K., Zolla-Pazner, S., Robinson, J., & Pinter, A. (2011). Characterization of structural features and diversity of variable-region determinants of related quaternary epitopes recognized by human and rhesus macaque monoclonal antibodies possessing unusually potent neutralizing activities. Journal of virology, 85 20, 10730-40 .
ELISA
Figure 2 Effect of variable loop deletion on virion capture by human and rhesus MAbs.
SF162-derived virions without or with deletions in the V1, V2, or V3 loop (DV1, DV2, or DV3, respectively) were added to ELISA wells coated with the indicated MAbs. MAbs 2909, 3.9F, and IgGb12 are human MAbs directed to quaternary epitope, V3, and CD4-binding domain, respectively.
Robinson, J. E., Franco, K., Elliott, D., Maher, M. J., Reyna, A. A., Montefiori, D. C., ... & Stamatatos, L. (2010). Quaternary Epitope Specificities of Anti-HIV-1 Neutralizing Antibodies Generated in Rhesus Macaques Infected by the Simian/Human Immunodeficiency Virus SHIVSF162P4. Journal of Virology, 84(7), 3443-3453.
Specifications
- Host Species
- Monkey
- Type
- Monkey IgG
- Specificity
- Recognizes HIV-1 gp120
- Species Reactivity
- HIV-1
- Clone
- LV23
- Applications
- ELISA, Neut
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Neutralization and Enzyme-Linked Immunosorbent Assay.
Target
- Alternative Names
- Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope
- UniProt ID
- P19550
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone LV23"
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Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABG-082 | Recombinant Anti-HIV-1 gp120 VHH Single Domain Antibody | ELISA, IHC, FC, FuncS | Llama VHH |
| MRO-028LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91C2) | ELISA | Single domain antibody |
| MRO-029LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91F10) | ELISA | Single domain antibody |
| MRO-030LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91E1) | ELISA | Single domain antibody |
| MRO-031LC-VHH | Anti-HIV-1 gp120 Recombinant Antibody (L91B5) | ELISA | Single domain antibody |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-125LC | Anti-HIV-1 gp120 Recombinant Antibody (N6) | Neut, ELISA | Human antibody |
| MRO-130LC | Human Anti-HIV-1 gp120 Recombinant Antibody (MRO-130LC) | ELISA, Neut, SPR | Human IgG |
| MRO-136LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900973) | ELISA | Human antibody |
| MRO-137LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900972) | ELISA | Human antibody |
| MRO-138LC | Anti-HIV-1 gp120 Recombinant Antibody (Ab900990) | ELISA | Human antibody |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-135LC | Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) | ELISA, WB, Neut | Chimeric antibody (mouse/human) |
| MRO-135LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
| MRO-135LC-F(E) | Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) | ELISA, WB | Chimeric antibody (mouse/human) |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-041LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (D59/A2) | ELISA | Mouse antibody |
| MRO-042LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (F58/H3) | ELISA | Mouse antibody |
| MRO-043LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (P1/D12) | ELISA | Mouse antibody |
| MRO-044LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (P4/D10) | ELISA | Mouse antibody |
| MRO-045LC-S(P) | Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (A47/B1) | ELISA | Mouse antibody |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4220 | Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) | WB, ELISA | Rabbit IgG |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-4375CQ | Recombinant Llama Anti-HIV-1 gp120 Single Domain Antibody (JM5) | ELISA, FC | Camelid VHH |
| MRO-4376CQ | Recombinant Llama Anti-HIV-1 gp120 Single Domain Antibody (JM7) | ELISA, Inhib | Camelid VHH |
| MRO-4377CQ | Recombinant Llama Anti-HIV-1 gp120 Single Domain Antibody (3E3) | ELISA, Neut | Camelid VHH |
| MRO-4378CQ | Recombinant Llama Anti-HIV-1 gp120 Single Domain Antibody (A14) | ELISA, Neut | Camelid VHH |
| MRO-4379CQ | Recombinant Llama Anti-HIV-1 gp120 Single Domain Antibody (B21) | ELISA, Neut | Camelid VHH |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MRO-3229CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone N5-i8); Fab Fragment | Neut, ELISA | Human Fab |
| MRO-3230CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone N5-i9); Fab Fragment | Neut, ELISA | Human Fab |
| MRO-3231CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PGDM14); Fab Fragment | ELISA, Neut | Human Fab |
| MRO-3248CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC21.01); Fab Fragment | ELISA, Neut | Human Fab |
| MRO-3249CQ-F(E) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone VRC21.02); Fab Fragment | ELISA, Neut | Human Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-S0050-YC-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone 3792); scFv Fragment | ELISA | Human scFv |
| FAMAB-0058WJ-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone P20); scFv Fragment | ELISA, Neut | Human scFv |
| HPAB-0714-YJ-S(P) | Monkey Anti-gp120 Recombinant Antibody (GE443); scFv Fragment | ELISA | Monkey scFv |
| HPAB-0716-YJ-S(P) | Monkey Anti-gp120 Recombinant Antibody (2S1H3); scFv Fragment | ELISA, IHC | Monkey scFv |
| PSBS-0130 | Human Anti-HIV-1 gp120 Recombinant Antibody (Clone VRC01cHuGL2); scFv Fragment | ELISA, FuncS | Human scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-101-S(P) | Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment | WB, ELISA, FuncS | Human scFv |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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