Anti-HIV-1 gp120 Recombinant Antibody (CAG1-51-4) (CAT#: MRO-135LC)

This product is a recombinant chimeric (mouse/human) anti-HIV-1 monoclonal antibody. CAG1-51-4 specifically binds to CD4 binding site of gp120 and can be potentially used in the treatment of acquired immunodeficiency syndrome (AIDS), a condition in humans characterized by clinical features including wasting syndromes, central nervous system degeneration and profound immunosuppression that results in life-threatening opportunistic infections and malignancies.

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Figure 1 shows the neutralizing activities of chimeric antibody on the infection of H9 cells by HIV-1.

Figure 1 shows the neutralizing activities of chimeric antibody on the infection of H9 cells by HIV-1.

Cell-free culture supernatants were col¬ lected at day 14 for HIV-1 specific antigen capture assays after the H9 cells were challenged with HIV-1 in the absence and in the presence of antibody tested. Each concentration of the antibodies was tested in triplicate. The inhibition of HIV-1 infection was calculated by comparing the optical densities obtained in the antigen capture assays of cultures infected with the virus in the presence of antibody to the negative control without added antibody. The antibodies tested were BAT123 (O), Chimeric antibody cAGl-51-4 (•), and a non-reactive murine anti-hcG antibody (Δ). Deta iled Des cription of the Invention.


  • Host Species
  • Human
  • Derivation
  • Chimeric (mouse/human)
  • Type
  • Chimeric antibody (mouse/human)
  • Specificity
  • HIV-1
  • Clone
  • CAG1-51-4
  • Applications
  • ELISA, WB, Neut
  • Related Disease
  • AIDS


  • Application Notes
  • The HIV-1 gp120 antibody has been reported in applications of Enzyme-linked Immunosorbent Assay, Western Blot, Neutralization.


  • Alternative Names
  • Human immunodeficiency virus type 1; HIV-1; Envelope glycoprotein GP120; gp120; HIV envelope

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.


Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone CAG1-51-4"

See other products for "HIV-1 gp120"

Chimeric Antibody

CAT Product Name Application Type
MRO-135LC-S(P) Anti-HIV-1 gp120 Recombinant Antibody scFv Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)
MRO-135LC-F(E) Anti-HIV-1 gp120 Recombinant Antibody Fab Fragment (CAG1-51-4) ELISA, WB Chimeric antibody (mouse/human)

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-4220 Rabbit Anti-HIV-1 gp120 Recombinant Antibody (clone SI299DS) WB, ELISA Rabbit IgG

Humanized Antibody

CAT Product Name Application Type
PABX-101-S(P) Human Anti-HIV-1 gp120 Recombinant Antibody (clone PG9); scFv Fragment WB, ELISA, FuncS Human scFv

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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