Recombinant human antibody to gp41. m46 binds to a conformational epitope on gp41 and did not compete with 2F5, 4E10 or Z13. It can bind to a 5 helix bundle, but not to N-heptad repeat coil-coils or a 6-helix bundle. It is broadly neutralizing.
Figure 1 Immunoprecipitation screen of the M series monoclonal antibodies.
Ad5-infected HeLa cells were labeled with methionine 14 to 18 h postinfection.
Harlow, E., Franza, B. R., & Schley, C. A. R. O. L. (1985). Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in early region 1A products. Journal of virology, 55(3), 533-546.
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• Increased sensitivity
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• High repeatability
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CAT | Product Name | Application | Type |
---|---|---|---|
PABL-185 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8062) | WB, ELISA, FuncS | Human IgG |
PABL-186 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5) | WB, Neut, FuncS | Human IgG |
PABL-187 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC176) | Neut, FuncS | Human IgG |
PABL-188 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 3BC315) | Neut, FuncS | Human IgG |
PABL-189 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone m66) | Neut, FuncS | Human IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBL-185 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 8062); Fab Fragment | WB, ELISA, FuncS | Human Fab |
PFBL-186 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone 2F5); Fab Fragment | WB, Neut, FuncS | Human Fab |
PFBZ-068 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1583); Fab Fragment | Neut | Mouse Fab |
PFBW-068 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone D5); Fab Fragment | WB, ELISA | Human Fab |
PFBC-069 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone HK20); Fab Fragment | Neut, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBZ-068 | Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1583); scFv Fragment | Neut | Mouse scFv |
PSBW-068 | Human Anti-HIV-1 gp41 Recombinant Antibody (clone D5); scFv Fragment | WB, ELISA | Human scFv |
PSBS-0051 | Monkey Anti-HIV-1 gp41 Recombinant Antibody (Clone DH570.4); scFv Fragment | ELISA, Neut, FuncS | Monkey scFv |
PSBS-0052 | Monkey Anti-HIV-1 gp41 Recombinant Antibody (Clone DH570.9); scFv Fragment | ELISA, FuncS | Monkey scFv |
PSBS-0053 | Monkey Anti-HIV-1 gp41 Recombinant Antibody (Clone DH570.mut58); scFv Fragment | ELISA, Neut, FuncS | Monkey scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
MRO-025LC | Anti-HIV-1 gp41 Recombinant Antibody (4E10-IgG3) | ELISA | Human antibody |
MRO-026LC | Anti-HIV-1 gp41 Recombinant Antibody (4E10-IgG1) | ELISA | Human antibody |
MRO-025LC-F(E) | Anti-HIV-1 gp41 Recombinant Antibody Fab Fragment (4E10-IgG3) | ELISA | Human antibody |
MRO-026LC-F(E) | Anti-HIV-1 gp41 Recombinant Antibody Fab Fragment (4E10-IgG1) | ELISA | Human antibody |
MRO-040LC-F(E) | Anti-HIV-1 gp41 Recombinant Antibody Fab Fragment (M66.6) | ELISA | Human antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
MHC-LC746 | A*2402/HIV-1 gp41 (RYLKDQQLL) MHC Tetramer | FCM |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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