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HIV-1 gp41
Anti-HIV-1 gp41 Recombinant Antibody Products
- Recombinant Anti-HIV-1 gp41 Antibody (MOB-486)
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- Derivation: Mouse
- Species Reactivity: HIV
- Type: IgG
- Application: WB, Dot, FuncS
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- Recombinant Human Anti-HIV-1 gp41 Soluble TCR () (KIH) (VS-0622-YF5553)
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- Species Reactivity: HIV-1
- Epitope: ERYLKDQQL
- MHC: HLA-B14
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- Recombinant Human Anti-HIV-1 gp41 Soluble TCR () (C-Cys) (VS-0622-YF2845)
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- Species Reactivity: HIV-1
- Epitope: ERYLKDQQL
- MHC: HLA-B14
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- Human Anti-HIV-1 gp41 Recombinant Antibody (HPAB-0735-WJ) (HPAB-0735-WJ)
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- Species Reactivity: HIV
- Type: Human IgG
- Application: ELISA, FuncS, WB
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- Rabbit Anti-HIV-1 gp41 Recombinant Antibody (clone 8K8); Fab Fragment (MRO-4201CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Rabbit Fab
- Application: ELISA, Neut
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- Rabbit Anti-HIV-1 gp41 Recombinant Antibody (clone R3); Fab Fragment (MRO-4202CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Rabbit Fab
- Application: ELISA
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- Rabbit Anti-HIV-1 gp41 Recombinant Antibody (clone R7); Fab Fragment (MRO-4203CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Rabbit Fab
- Application: ELISA
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- Rabbit Anti-HIV-1 gp41 Recombinant Antibody (clone R21); Fab Fragment (MRO-4204CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Rabbit Fab
- Application: ELISA
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 9303); Fab Fragment (MRO-4195CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: WB, FC
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 3H6); Fab Fragment (MRO-4196CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone D17); Fab Fragment (MRO-4197CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA, WB
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone D40); Fab Fragment (MRO-4198CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA, WB
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- Rabbit Anti-HIV-1 gp41 Recombinant Antibody (clone 13K3); Fab Fragment (MRO-4200CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Rabbit Fab
- Application: ELISA
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone T9); Fab Fragment (MRO-4189CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: Neut
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone D12); Fab Fragment (MRO-4190CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: Neut, ELISA
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone WR102); Fab Fragment (MRO-4191CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone WR204); Fab Fragment (MRO-4192CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone WR301); Fab Fragment (MRO-4193CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone T30); Fab Fragment (MRO-4183CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: WB
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone T4); Fab Fragment (MRO-4184CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: Neut, ELISA
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone D16); Fab Fragment (MRO-4185CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA, Neut
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone P3G9); Fab Fragment (MRO-4186CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA, Neut
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone P4A3); Fab Fragment (MRO-4187CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone P4C2); Fab Fragment (MRO-4188CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 9F2); Fab Fragment (MRO-4177CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 9G8); Fab Fragment (MRO-4178CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA, FC, WB
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone D43); Fab Fragment (MRO-4179CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA, WB
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 127); Fab Fragment (MRO-4180CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA, WB, Block
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone T26); Fab Fragment (MRO-4181CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA, Block
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone T3); Fab Fragment (MRO-4182CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA, WB
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- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1c11); Fab Fragment (MRO-4171CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1d9); Fab Fragment (MRO-4172CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 2G8); Fab Fragment (MRO-4173CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 32G4); Fab Fragment (MRO-4174CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 35-1); Fab Fragment (MRO-4175CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: Neut
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 37F6); Fab Fragment (MRO-4176CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
Compare
- Human Anti-HIV-1 gp41 Recombinant Antibody (clone K14); Fab Fragment (MRO-4165CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-HIV-1 gp41 Recombinant Antibody (clone 13B2); Fab Fragment (MRO-4166CQ-F(E))
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- Derivation: Humanized
- Species Reactivity: HIV-1
- Type: Humanized Fab
- Application: ELISA
Compare
- Monkey Anti-HIV-1 gp41 Recombinant Antibody (clone DH570); Fab Fragment (MRO-4167CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Monkey Fab
- Application: ELISA, Neut, FC
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 1-2); Fab Fragment (MRO-4169CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: Neut
Compare
- Mouse Anti-HIV-1 gp41 Recombinant Antibody (clone 17C8); Fab Fragment (MRO-4170CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Mouse Fab
- Application: ELISA
Compare
- Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10-1487); Fab Fragment (MRO-4159CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-HIV-1 gp41 Recombinant Antibody (clone 10-437); Fab Fragment (MRO-4160CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Human Fab
- Application: Neut
Compare
- Human Anti-HIV-1 gp41 Recombinant Antibody (clone 1342); Fab Fragment (MRO-4163CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-HIV-1 gp41 Recombinant Antibody (clone N2-4); Fab Fragment (MRO-4164CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Human Fab
- Application: ELISA, RIA, WB
Compare
- Human Anti-HIV-1 gp41 Recombinant Antibody (clone KU32); Fab Fragment (MRO-4148CQ-F(E))
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- Species Reactivity: HIV-1
- Type: Human Fab
- Application: ELISA
Compare
- Human Anti-HIV-1 gp41 Recombinant Antibody; Fab Fragment (HPAB-0735-WJ-F(E)) (HPAB-0735-WJ-F(E))
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- Species Reactivity: HIV
- Type: Human Fab
- Application: Neut
Compare
- Human Anti-HIV-1 gp41 Recombinant Antibody; scFv Fragment (HPAB-0735-WJ-S(P)) (HPAB-0735-WJ-S(P))
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- Species Reactivity: HIV
- Type: Human scFv
- Application: Neut
Compare
- Recombinant Human Anti-HIV-1 gp41 Antibody Fab Fragment (MHH-486-F(E))
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- Derivation: Human
- Species Reactivity: HIV
- Type: Fab
- Application: ELISA, IP, FuncS
Compare
- Recombinant Human Anti-HIV-1 gp41 Antibody scFv Fragment (MHH-486-S(P))
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- Derivation: Human
- Species Reactivity: HIV
- Type: scFv
- Application: IF, Neut, FuncS
Compare
- Recombinant Anti-HIV-1 gp41 Antibody Fab Fragment (MOB-486-F(E))
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- Derivation: Mouse
- Species Reactivity: HIV
- Type: Fab
- Application: ELISA, FacS, FuncS
Compare
- Recombinant Anti-HIV-1 gp41 Antibody scFv Fragment (MOB-486-S(P))
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- Derivation: Mouse
- Species Reactivity: HIV
- Type: scFv
- Application: FC, WB, FuncS
Compare
- Human Anti-HIV-1 gp41 (clone A2) scFv-Fc Chimera (VS-0325-FY129)
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- Species Reactivity: Human immunodeficiency virus 1 (HIV-1)
- Type: Human IgG1, scFv-Fc
- Application: Neut, ADCC
Compare
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For Research Use Only. Not For Clinical Use.
The human immunodeficiency virus (HIV) is a lentivirus (a subgroup of retrovirus) that causes HIV infection and over time acquired immunodeficiency syndrome (AIDS).
gp41 acts as a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During fusion of viral and target intracellular membranes, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. Complete fusion occurs in host cell endosomes and is dynamin-dependent, however some lipid transfer might occur at the plasma membrane. The virus undergoes clathrin-dependent internalization long before endosomal fusion, thus minimizing the surface exposure of conserved viral epitopes during fusion and reducing the efficacy of inhibitors targeting these epitopes. Membranes fusion leads to delivery of the nucleocapsid into the cytoplasm.