Recombinant monoclonal antibody specially binds to tick-borne encephalitis virus. This mouse anti-TBEV monoclonal antibody 10C2 could be potencially used in the treatment of Tick-borne encephalitis.
Figure 1 Western blot of a lysate of TBEV-infected cells was prepared.
Reactivity of mouse sera with TBEV proteins.
Kreil, T. R., Maier, E., Fraiss, S., & Eibl, M. M. (1998). Neutralizing antibodies protect against lethal flavivirus challenge but allow for the development of active humoral immunity to a nonstructural virus protein. Journal of virology, 72(4), 3076-3081.
Figure 2 Active immunity to TBEV. Female BALB/c mice were administered s.c. 0.2 ml of a 1:10-diluted human TBEV Ig preparation 2 h before they were injected i.p. with different amounts of TBEV.
Differences in the survival of groups of mice were compared to the survival of mice which received UV-inactivated TBEV instead of the initial TBEV challenge by a two-sided log-rank test, and significances are indicated by asterisks.
Kreil, T. R., Maier, E., Fraiss, S., & Eibl, M. M. (1998). Neutralizing antibodies protect against lethal flavivirus challenge but allow for the development of active humoral immunity to a nonstructural virus protein. Journal of virology, 72(4), 3076-3081.
Figure 3 Brain, thalamus, severe lymphohistiocytic perivascular infiltration of neuroparenchyma and gliosis.
Original magnification ×200.
Böhm, B., Schade, B., Bauer, B., Hoffmann, B., Hoffmann, D., Ziegler, U., ... & Böttcher, J. (2017). Tick-borne encephalitis in a naturally infected sheep. BMC veterinary research, 13(1), 267.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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CAT | Product Name | Application | Type |
---|---|---|---|
PABC-437 | Recombinant Mouse Anti-TBEV Antibody (19/1786) | Neut | Mouse IgG1 |
FAMAB-0132JF | Mouse Anti-TBEV Recombinant Antibody (clone 13D6) | WB, ELISA, IHC | Mouse IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBC-437 | Recombinant Mouse Anti-TBEV Antibody Fab Fragment (19/1786) | Neut | Mouse Fab |
FAMAB-0132JF-F(E) | Mouse Anti-TBEV Recombinant Antibody (clone 13D6); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
FAMAB-0133JF-F(E) | Mouse Anti-TBEV Recombinant Antibody (clone 10C2); Fab Fragment | WB, ELISA, FuncS | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBC-437 | Recombinant Mouse Anti-TBEV Antibody scFv Fragment (19/1786) | Neut | Mouse scFv |
FAMAB-0132JF-S(P) | Mouse Anti-TBEV Recombinant Antibody (clone 13D6); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
FAMAB-0133JF-S(P) | Mouse Anti-TBEV Recombinant Antibody (clone 10C2); scFv Fragment | WB, ELISA, FuncS | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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