Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0703-YJ-VHH) (CAT#: HPAB-0703-YJ-VHH)
This product is a recombinant Camel single domain antibody that recognizes Human TNFRSF10B. It could be potential candidates to trigger apoptosis in various cancer cells.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Cerebral cortex
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51170_B_7_5.jpg
(Endothelial cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Neuropil
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51170_B_7_5.jpg
Figure 2 Colon
(Endothelial cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_3.jpg
(Endothelial cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Glandular cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_3.jpg
Figure 3 Liver
(Cholangiocytes
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Hepatocytes
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_4.jpg
(Cholangiocytes
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous
Hepatocytes
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_4.jpg
Figure 4 Kidney
(Cells in glomeruli
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_8_5.jpg
(Cells in glomeruli
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Cells in tubules
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_8_5.jpg
Figure 5 Testis
(Cells in seminiferous ducts
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Leydig cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_6_6.jpg
(Cells in seminiferous ducts
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous
Leydig cells
Staining:
High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_6_6.jpg
Figure 6 Lymph node
(Non-germinal center cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_8.jpg
(Non-germinal center cells
Staining:
Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/23625/51179_A_9_8.jpg
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000120889-TNFRSF10B
(Cell lines ordered by descending RNA expression order.)
* https://v21.proteinatlas.org/ENSG00000120889-TNFRSF10B
Figure 7 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120889-TNFRSF10B
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120889-TNFRSF10B
Specifications
- Immunogen
- Hapten-peptide 1ITQQDLAPQQRA12
- Host Species
- Camelid
- Type
- Camelid VHH
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- HPAB-0703-YJ-VHH
- Applications
- ELISA, Apop
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Apoptosis.
Target
- Alternative Names
- DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; tumor necrosis factor receptor superfamily member 10B; Fas-like protein; TNF-related apoptosis-inducing ligand receptor 2; apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; p53-regulated DNA damage-inducible cell death receptor(killer); tumor necrosis factor receptor superfamily, member 10b; tumor necrosis factor receptor-like protein ZTNFR9
- Gene ID
- 8795
- UniProt ID
- O14763
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "TNFRSF10B"
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NABL-052 | Recombinant Anti-human TNFRSF10B VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
| HPAB-0704-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0704-YJ-VHH) | ELISA | Camelid VHH |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-203 | Human Anti-TNFRSF10B Recombinant Antibody (TAB-203) | ELISA, IP, FC, FuncS, Neut, IF, ICC | Human IgG1, κ |
| TAB-195 | Anti-Human TRAIL-R2 Recombinant Antibody (Lexatumumab) | ELISA, IP, FC, FuncS, Neut, IF, ICC | IgG1 - lambda |
| TAB-253MZ | Anti-Human TNFRSF10B Recombinant Antibody (AU11) | ELISA, FuncS | Human antibody |
| TAB-254MZ | Anti-Human TNFRSF10B Recombinant Antibody (AU12) | ELISA, FuncS | Human antibody |
| TAB-253MZ-F(E) | Anti-Human TNFRSF10B Recombinant Antibody Fab Fragment (AU11) | FC, ELISA | Human antibody |
Rat Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-625CL | Human Anti-TNFRSF10B Recombinant Antibody (TAB-625CL) | ELISA | Single Domain Antibody |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-029 | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment | WB, ELISA, FuncS | Human Fab |
| PFBL-030 | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (PFBL-030) | WB, ELISA, FuncS | Human Fab |
| PFBW-057 | Human Anti-TNFRSF10B Recombinant Antibody (clone YSd1); Fab Fragment | ELISA | Human Fab |
| PFBC-123 | Human Anti-TNFRSF10B Recombinant Antibody (clone BDF1); Fab Fragment | ELISA | Human Fab |
| HPAB-0303-YC-F(E) | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (HPAB-0303-YC-F(E)) | ELISA, FuncS | Humanized Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBW-057 | Human Anti-TNFRSF10B Recombinant Antibody (clone YSd1); scFv Fragment | ELISA | Human scFv |
| PSBC-123 | Human Anti-TNFRSF10B Recombinant Antibody (clone BDF1); scFv Fragment | ELISA | Human scFv |
| HPAB-0412-CN-S(P) | Human Anti-TNFRSF10B Recombinant Antibody; scFv Fragment (HPAB-0412-CN-S(P)) | WB, ELISA | Human scFv |
| HPAB-0941-FY-F(E) | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (HPAB-0941-FY-F(E)) | ELISA | Human Fab |
| HPAB-2047-FY-S(P) | Human Anti-TNFRSF10B Recombinant Antibody; scFv Fragment (HPAB-2047-FY-S(P)) | IA | Human scFv |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-250MZ | Human Anti-TNFRSF10B Recombinant Antibody (TAB-250MZ) | FuncS | Humanized IgG |
| TAB-250MZ-S(P) | Human Anti-TNFRSF10B Recombinant Antibody; scFv Fragment (TAB-250MZ-S(P)) | FC, ELISA | Humanized scFv |
| TAB-251MZ-S(P) | Human Anti-TNFRSF10B Recombinant Antibody; scFv Fragment (TAB-251MZ-S(P)) | FC, ELISA | Humanized scFv |
| TAB-250MZ-F(E) | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (TAB-250MZ-F(E)) | FC, ELISA | Humanized Fab |
| TAB-251MZ-F(E) | Human Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (TAB-251MZ-F(E)) | FC, ELISA | Humanized Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-247MZ-S(P) | Mouse Anti-TNFRSF10B Recombinant Antibody; scFv Fragment (TAB-247MZ-S(P)) | ELISA, WB | Mouse scFv |
| TAB-248MZ-S(P) | Mouse Anti-TNFRSF10B Recombinant Antibody; scFv Fragment (TAB-248MZ-S(P)) | FC, ELISA | Mouse scFv |
| TAB-249MZ-S(P) | Mouse Anti-TNFRSF10B Recombinant Antibody; scFv Fragment (TAB-249MZ-S(P)) | FC, ELISA | Mouse scFv |
| TAB-252MZ-S(P) | Anti-Human TNFRSF10B Recombinant Antibody scFv Fragment | ELISA | |
| TAB-247MZ-F(E) | Mouse Anti-TNFRSF10B Recombinant Antibody; Fab Fragment (TAB-247MZ-F(E)) | ELISA, WB | Mouse Fab |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3604 | Rabbit Anti-TNFRSF10B Recombinant Antibody (clone DS3604AB), PE | FC, WB | Rabbit IgG |
| MOR-3605 | Rabbit Anti-Tnfrsf10b Recombinant Antibody (clone DS3605AB) | ELISA | Rabbit IgG |
| MOR-4468 | Rabbit Anti-Tnfrsf10b Recombinant Antibody (clone SI562DS) | ELISA | Rabbit IgG |
| MOR-4469 | Rabbit Anti-TNFRSF10B Recombinant Antibody (clone SI563DS) | ELISA, FC | Rabbit IgG |
| MOR-4473 | Rabbit Anti-TNFRSF10B Recombinant Antibody (clone SI567DS) | FC | Rabbit IgG |
Agonistic Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-104LC | Human Anti-TNFRSF10B Recombinant Antibody (MOB-104LC) | FuncS | Chimeric (mouse/human) IgG1, κ |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0303-YC | Human Anti-TNFRSF10B Recombinant Antibody (HPAB-0303-YC) | ELISA, FuncS, Inhib | Humanized IgG1 |
| HPAB-0304-YC | Human Anti-TNFRSF10B Recombinant Antibody (HPAB-0304-YC) | FuncS | Human IgG |
| FN-235CQ | Hamster Anti-Tnfrsf10b Recombinant Antibody (clone MD5-1) | FC, FuncS | Hamster IgG |
| HPAB-1145WJ | Mouse Anti-TNFRSF10B Recombinant Antibody (clone E-11-13) | ELISA, FC | Mouse IgG1 |
| HPAB-1146WJ | Mouse Anti-TNFRSF10B Recombinant Antibody (clone L-30-10) | ELISA, FC | Mouse IgG1 |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-196 | Afuco™ Anti-TNFRSF10B ADCC Recombinant Antibody (Tigatuzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-203 | Afuco™ Anti-TNFRSF10B Recombinant Antibody (AFC-TAB-203), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | Human IgG1, κ |
| AFC-TAB-180 | Afuco™ Anti-TNFRSF10B ADCC Recombinant Antibody (Drozitumab), ADCC Enhanced | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-195 | Afuco™ Anti-TNFRSF10B ADCC Recombinant Antibody (Lexatumumab), ADCC Enhanced | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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