This antibody is an anti-DR5 antibody with improved affinity that specifically binds to the death receptor 5 (DR5) to destroy cancer cells effectively.
Figure 1 shows the results of measuring the stability of AU11 and AU12.
Figure 2 is a diagram shows the result of measuring the same antigen binding site between HW1 and AU11 or AU12 using a competitive ELISA.
Figure 3 is a diagram shows the results of comparing and evaluating the degree of apoptosis of HW1, AU11, and AU12 in HCT116, a human colorectal cancer cell line by MTT-assay.
Figure 4 shows MTT-assay of apoptosis ability of HW1, AU11 and AU12 in the presence of various inhibitors (Z-VAD, SP600125, SB203580, 3-MA, Chloroguine) in human colon cancer cell line HCT116. It is a figure which shows the result of analysis.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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