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    Anti-Human TNFRSF10B Recombinant Antibody (AU11) (CAT#: TAB-253MZ)

    This antibody is an anti-DR5 antibody with improved affinity that specifically binds to the death receptor 5 (DR5) to destroy cancer cells effectively.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Other Requirements:
    We require custom production
    • Published Data
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    FuncS

    Figure 1 shows the results of measuring the stability of AU11 and AU12.

    Figure 1 shows the results of measuring the stability of AU11 and AU12.

    ELISA

    Figure 2 is a diagram shows the result of measuring the same antigen binding site between HW1 and AU11 or AU12 using a competitive ELISA.

    Figure 2 is a diagram shows the result of measuring the same antigen binding site between HW1 and AU11 or AU12 using a competitive ELISA.

    FuncS

    Figure 3 is a diagram shows the results of comparing and evaluating the degree of apoptosis of HW1, AU11, and AU12 in HCT116, a human colorectal cancer cell line by MTT-assay.

    Figure 3 is a diagram shows the results of comparing and evaluating the degree of apoptosis of HW1, AU11, and AU12 in HCT116, a human colorectal cancer cell line by MTT-assay.

    FuncS

    Figure 4 shows MTT-assay of apoptosis ability of HW1, AU11 and AU12 in the presence of various inhibitors (Z-VAD, SP600125, SB203580, 3-MA, Chloroguine) in human colon cancer cell line HCT116. It is a figure which shows the result of analysis.

    Figure 4 shows MTT-assay of apoptosis ability of HW1, AU11 and AU12 in the presence of various inhibitors (Z-VAD, SP600125, SB203580, 3-MA, Chloroguine) in human colon cancer cell line HCT116. It is a figure which shows the result of analysis.


    Specifications

    • Host Species
    • Human
    • Derivation
    • Antibody library
    • Type
    • Human antibody
    • Specificity
    • Human
    • Clone
    • AU11
    • Applications
    • ELISA, FuncS
    • Related Disease
    • Cancers caused by DR5 expression

    Applications

    • Application Notes
    • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Functional Assay.

    Target

    • Alternative Names
    • TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; tumor necrosis factor receptor superfamily member 10B; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; TNF receptor superfamily member 10b; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer)

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "Clone AU11"

    See other products for "TNFRSF10B"

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    Single Domain Antibodies Humanized Antibodies Human Antibodies Rat Antibodies IgG Antibodies ScFv Antibodies Fab Antibodies Mouse Antibodies Rabbit Monoclonal Antibodies Agonistic Antibodies ADCC Enhanced Antibodies ScFv-Fc Chimeras Extracellular Vesicle Antibodies IHC Kits & Antibodies Biparatopic Antibodies
    CAT Product Name Application Type
    NABL-052 Recombinant Anti-human TNFRSF10B VHH Single Domain Antibody WB, ELISA, IHC, FC, FuncS Llama VHH
    HPAB-0703-YJ-VHH Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0703-YJ-VHH) ELISA, Apop Camelid VHH
    HPAB-0704-YJ-VHH Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0704-YJ-VHH) ELISA Camelid VHH

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