Anti-Human TNFRSF10B Recombinant Antibody (AU11) (CAT#: TAB-253MZ)

This antibody is an anti-DR5 antibody with improved affinity that specifically binds to the death receptor 5 (DR5) to destroy cancer cells effectively.

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  • Gene Expression
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FuncS

Figure 1 shows the results of measuring the stability of AU11 and AU12.

Figure 1 shows the results of measuring the stability of AU11 and AU12.

ELISA

Figure 2 is a diagram shows the result of measuring the same antigen binding site between HW1 and AU11 or AU12 using a competitive ELISA.

Figure 2 is a diagram shows the result of measuring the same antigen binding site between HW1 and AU11 or AU12 using a competitive ELISA.

FuncS

Figure 3 is a diagram shows the results of comparing and evaluating the degree of apoptosis of HW1, AU11, and AU12 in HCT116, a human colorectal cancer cell line by MTT-assay.

Figure 3 is a diagram shows the results of comparing and evaluating the degree of apoptosis of HW1, AU11, and AU12 in HCT116, a human colorectal cancer cell line by MTT-assay.

FuncS

Figure 4 shows MTT-assay of apoptosis ability of HW1, AU11 and AU12 in the presence of various inhibitors (Z-VAD, SP600125, SB203580, 3-MA, Chloroguine) in human colon cancer cell line HCT116. It is a figure which shows the result of analysis.

Figure 4 shows MTT-assay of apoptosis ability of HW1, AU11 and AU12 in the presence of various inhibitors (Z-VAD, SP600125, SB203580, 3-MA, Chloroguine) in human colon cancer cell line HCT116. It is a figure which shows the result of analysis.


Specifications

  • Host Species
  • Human
  • Derivation
  • Antibody library
  • Type
  • Human antibody
  • Specificity
  • Human
  • Clone
  • AU11
  • Applications
  • ELISA, FuncS
  • Related Disease
  • Cancers caused by DR5 expression

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Functional Assay.

Target

  • Alternative Names
  • TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; tumor necrosis factor receptor superfamily member 10B; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; TNF receptor superfamily member 10b; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer)

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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