Anti-Human TNFRSF10B Recombinant Antibody (AU11) (CAT#: TAB-253MZ)
This antibody is an anti-DR5 antibody with improved affinity that specifically binds to the death receptor 5 (DR5) to destroy cancer cells effectively.
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
Figure 1 shows the results of measuring the stability of AU11 and AU12.
Figure 2 is a diagram shows the result of measuring the same antigen binding site between HW1 and AU11 or AU12 using a competitive ELISA.
Figure 3 is a diagram shows the results of comparing and evaluating the degree of apoptosis of HW1, AU11, and AU12 in HCT116, a human colorectal cancer cell line by MTT-assay.
Figure 4 shows MTT-assay of apoptosis ability of HW1, AU11 and AU12 in the presence of various inhibitors (Z-VAD, SP600125, SB203580, 3-MA, Chloroguine) in human colon cancer cell line HCT116. It is a figure which shows the result of analysis.
Specifications
- Host Species
- Human
- Derivation
- Antibody library
- Type
- Human antibody
- Specificity
- Human
- Clone
- AU11
- Applications
- ELISA, FuncS
- Related Disease
- Cancers caused by DR5 expression
Applications
- Application Notes
- This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Functional Assay.
Target
- Alternative Names
- TNFRSF10B; tumor necrosis factor receptor superfamily, member 10b; DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; tumor necrosis factor receptor superfamily member 10B; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; TNF receptor superfamily member 10b; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer)
- Gene ID
- 8795
- UniProt ID
- O14763
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone AU11"
See other products for "TNFRSF10B"
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CAT | Product Name | Application | Type |
---|---|---|---|
NABL-052 | Recombinant Anti-human TNFRSF10B VHH Single Domain Antibody | WB, ELISA, IHC, FC, FuncS | Llama VHH |
HPAB-0703-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0703-YJ-VHH) | ELISA, Apop | Camelid VHH |
HPAB-0704-YJ-VHH | Camelid Anti-TNFRSF10B Recombinant Single Domain Antibody (HPAB-0704-YJ-VHH) | ELISA | Camelid VHH |
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For Research Use Only. Not For Clinical Use.
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