Rat Anti-TNFRSF17 Recombinant Antibody (clone SG16.17) (CAT#: HPAB-M0232-YC)

Purified SG16.17 displayed improved blocking activity across similar concentrations when compared to the commercial antibody. SG-16.45 showed dose-dependent inhibition of April binding although not as strongly as SG-16.17.


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Inhib

Figure 1 shows inhibiton of APRIL blocking titrated with anti-BCMA antibodies.

Figure 1 shows inhibiton of APRIL blocking titrated with anti-BCMA antibodies.

ELISA

Figure 3 shows competition binding assay showing binding of chimeric SG16.17 to human FcRIIIa.

Figure 3 shows competition binding assay showing binding of chimeric SG16.17 to human FcRIIIa.

FuncS

Figure 2 provides ADCC activity of the SG16.17 SEA antibody on MM1R target cells.

Figure 2 provides ADCC activity of the SG16.17 SEA antibody on MM1R target cells.


Specifications

  • Host Species
  • Rat
  • Type
  • Rat IgG
  • Specificity
  • Human TNFRSF17
  • Species Reactivity
  • Human
  • Clone
  • SG16.17
  • Applications
  • Inhib, ELISA, FuncS

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Buffer
  • PBS
  • Preservative
  • No preservatives
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

  • Application Notes
  • This antibody has been reported for use in Enzyme-Linked Immunosorbent Assay, Functional Assay and Inhibition.

Target

  • Alternative Names
  • TNF Receptor Superfamily Member 17; B-Cell Maturation Protein; BCMA; BCM; Tumor Necrosis Factor Receptor Superfamily, Member 17; Tumor Necrosis Factor Receptor Superfamily Member 17;

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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Recombinant Antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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