Mouse Anti-TNFRSF17 Recombinant Antibody (clone J22.9-xi); scFv Fragment

CAT#: PSBL-019

Recombinant Mouse Antibody (J22.9-xi) scFv Fragment is specific to BCMA, expressed in E. coli. The high affinity antibody fragment blocks the binding of the native ligands APRIL and BAFF to BCMA and effectively depletes MM cells in vitro and in vivo and substantially prolongs tumor-free survival under therapeutic conditions in a xenograft mouse model.

Gene Expression
Figure 1 RNA cell line category: Cell line enhanced (Karpas-707, RPMI-8226, U-266/70, U-266/84)

Specifications

  • Immunogen
  • Human tumor necrosis factor receptor superfamily, member 17
  • Host Species
  • Mouse
  • Type
  • Mouse scFv
  • Specificity
  • Human TNFRSF17
  • Species Reactivity
  • Human
  • Clone
  • J22.9-xi

Product Property

  • Purity
  • >95% as determined by SDS-PAGE and HPLC analysis
  • Concentration
  • Please refer to the vial label for the specific concentration.
  • Storage
  • Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • TNFRSF17; tumor necrosis factor receptor superfamily; member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein
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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

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COA

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