Anti-Yeast ALG6 Recombinant Antibody (clone 6AG9) (CAT#: PABS-0155)
This recombinant monoclonal antibody to Yeast ALG6 is a Synthetic construct monoclonal antibody that can be used for applications: ELISA. This product can increased the size and thermostability of detergent-solubilized ALG6 but did not interfere with its catalytic activity.
Specific Inquiry
Figure 1 ALG6-6AG9-Fab interactions.
Size-exclusion chromatography of purified ALG6 in detergent (64 kDa) in the presence and absence of 6AG9-Fab (49 kDa).
Bloch, J. S., Pesciullesi, G., Boilevin, J., Nosol, K., Irobalieva, R. N., Darbre, T., ... & Locher, K. P. (2020). Structure and mechanism of the ER-based glucosyltransferase ALG6. Nature, 579(7799), 443-447.
Figure 2 ALG6-6AG9-Fab interactions.
Analysis of ALG6 activity in the presence of 6AG9-Fab. 6AG9-Fab was incubated with ALG6 at a 5-fold or 15-fold molar excess to test inhibition. The lane labelled Man9-LLO is a control sample for size comparison.
Bloch, J. S., Pesciullesi, G., Boilevin, J., Nosol, K., Irobalieva, R. N., Darbre, T., ... & Locher, K. P. (2020). Structure and mechanism of the ER-based glucosyltransferase ALG6. Nature, 579(7799), 443-447.
Specifications
- Host Species
- Synthetic construct
- Derivation
- Phage display library
- Type
- Synthetic construct IgG
- Specificity
- Yeast ALG6
- Species Reactivity
- Yeast
- Clone
- 6AG9
- Applications
- ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Dolichyl-P-Glc:Man(9)GlcNAc(2)-PP-dolichol alpha-1; 3-glucosyltransferase
- Gene ID
- 854163
- UniProt ID
- Q12001
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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