Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins
Intracellular
Cell type enhanced (Cytotrophoblasts, Extravillous trophoblasts)
Low immune cell specificity
Low cell line specificity
Homodimer (PubMed:14756553, PubMed:14966129). Associates with internalized INSR complexes on Golgi/endosomal membranes (PubMed:25687571). Interacts with INSR; ATIC together with PRKAA2/AMPK2 and HACD3/PTPLAD1 is proposed to be part of a signaling network regulating INSR autophosphorylation and endocytosis (PubMed:25687571).
Hydrolase, Multifunctional enzyme, Transferase
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For Research Use Only. Not For Clinical Use.