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GABRR1

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene.
Protein class

Transporters

Predicted location

Membrane

Single cell type specificity

Cell type enriched (Bipolar cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Group enriched (NTERA-2, OE19, SuSa)

Interaction

Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1 (By similarity).

Molecular function

Chloride channel, Ion channel

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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