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SCARB1
The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]
Protein class
Metabolic proteins, Transporters
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enhanced (Hepatocytes, Adipocytes, Granulosa cells)
Immune cell specificity
Group enriched (plasmacytoid DC, myeloid DC, classical monocyte)
Cell line specificity
Cell line enhanced (RPMI-8226)
Interaction
The C-terminal region binds to PDZK1. (Microbial infection) Interacts with hepatitis C virus E1:E2 glycoproteins.
Molecular function
Host cell receptor for virus entry, Receptor
More Types Infomation
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
- Recombinant Mouse Anti-Scarb1 Antibody (CBL917) (NEUT-1927CQ)
-
- Species Reactivity: Rat
- Type: IgG1
- Application: FC, IHC, Neut
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC, IF, IHC
-
- Species Reactivity: Rat
- Application: FC, IHC-Fr, Neut
-
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, IHC, ICC
- Mouse Anti-SCARB1 Recombinant Antibody (HPAB-0384-CN) (HPAB-0384-CN)
-
- Species Reactivity: Human, Mouse
- Type: Mouse IgG1
- Application: ELISA, FC, IHC
- Mouse Anti-SCARB1 Recombinant Antibody; scFv Fragment (HPAB-0384-CN-S(P)) (HPAB-0384-CN-S(P))
-
- Species Reactivity: Human, Mouse
- Type: Mouse scFv
- Application: ELISA, FC, IHC
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IP
- Recombinant Human Anti-SCARB1 Antibody Fab Fragment (mAb15) (HPAB-1611-FY-S(P))
-
- Species Reactivity: HCV
- Type: Human Fab
- Application: Inhib, ELISA, FC
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB
- Recombinant Human Anti-SCARB1 Antibody Fab Fragment (mAb81) (HPAB-1610-FY-S(P))
-
- Species Reactivity: HCV
- Type: Human Fab
- Application: Inhib, ELISA
- Recombinant Human Anti-SCARB1 Antibody scFv Fragment (mAb15) (HPAB-1611-FY-F(E))
-
- Species Reactivity: HCV
- Type: Human scFv
- Application: Inhib, ELISA, FC
- Recombinant Human Anti-SCARB1 Antibody Fab Fragment (mAb8) (HPAB-1609-FY-S(P))
-
- Species Reactivity: HCV
- Type: Human Fab
- Application: Inhib, ELISA, FC
- Rabbit Anti-SCARB1 Recombinant Antibody (VS3-WK1073) (VS3-WK1073)
-
- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IHC, FC
- Recombinant Human Anti-SCARB1 Antibody scFv Fragment (mAb81) (HPAB-1610-FY-F(E))
-
- Species Reactivity: HCV
- Type: Human scFv
- Application: Inhib, ELISA
- Human Anti-SCARB1 Recombinant Antibody (clone scFVC11); Fab Fragment (HPAB-0298CQ-F(E))
-
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, FuncS
- Recombinant Human Anti-SCARB1 Antibody (mAb15) (HPAB-1611-FY)
-
- Species Reactivity: HCV
- Type: Human IgG4
- Application: Inhib, Neut, FC
- Recombinant Human Anti-SCARB1 Antibody (mAb81) (HPAB-1610-FY)
-
- Species Reactivity: HCV
- Type: Human IgG
- Application: Inhib, FC
- Mouse Anti-SCARB1 Recombinant Antibody; Fab Fragment (HPAB-0384-CN-F(E)) (HPAB-0384-CN-F(E))
-
- Species Reactivity: Human, Mouse
- Type: Mouse Fab
- Application: ELISA, FC, IHC
- Recombinant Human Anti-SCARB1 Antibody scFv Fragment (mAb8) (HPAB-1609-FY-F(E))
-
- Species Reactivity: HCV
- Type: Human scFv
- Application: Inhib, ELISA, FC
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