Recombinant Human Anti-SCARB1 Antibody (mAb15) (CAT#: HPAB-1611-FY)
This product is a recombinant antibody that recognizes SCARB1. The monoclonal antibody mAb15 reacts with the epitope of SCARB1. The antibody is capable of inhibiting a HCV virus to bind to the SR-B 1 receptor.
Specific Inquiry
Inhib
Figure 1 HCVcc infection inhibited by anti-SRBl mAb measured by q-PCR.
Neut
Figure 2 Neutralization of J6/JFH1 HCVcc infection by anti-SR-Bl mAbs.
Huh7.5 cells were infected with HCVcc upon pre-incubation with increasing concentrations (ng/ml) of anti-SR-Bl mAbs. Infectivity was measured 3 days post-infection.
FC
Figure 3 Apparent affinity of anti-SRBl mAbs.
FC
Figure 4 Binding to HepG2 cells of various antiSR-BI mAbs.
Binding of anti-SR-BI mAbs to HepG2 cells as measured by flow cytometry. Values on the vertical axis are MFIs and on the horizontal axis are concentrations (ng/ml) of anti-SR-BI mAbs on a logarithmic scale.
Lacek, K., Vercauteren, K., Grzyb, K., Naddeo, M., Verhoye, L., Słowikowski, M. P., ... & Leroux-Roels, G. (2012). Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice. Journal of hepatology, 57(1), 17-23.
Neut
Figure 5 Neutralization of HCVcc by anti-SR-BI mAbs as measured by SEAP assay.
Huh7-J20 cells were infected with HCVcc upon pre-incubation with increasing concentrations (ng/ml) of anti-SR-BI mAbs (indicated on the horizontal axis on a logarithmic scale).
Lacek, K., Vercauteren, K., Grzyb, K., Naddeo, M., Verhoye, L., Słowikowski, M. P., ... & Leroux-Roels, G. (2012). Novel human SR-BI antibodies prevent infection and dissemination of HCV in vitro and in humanized mice. Journal of hepatology, 57(1), 17-23.
Specifications
- Host Species
- Human
- Type
- Human IgG4
- Specificity
- HCV SCARB1
- Species Reactivity
- HCV
- Clone
- mAb15
- Applications
- Inhib, Neut, FC
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Store at -20°C for long-term storage. Avoid freeze/thaw cycles.
Applications
- Application Notes
- The SCARB1 antibody has been reported in applications of Inhibition, Neutralization, Flow Cytometry.
Target
- Alternative Names
- Scavenger Receptor Class B Member 1; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor)-Like 1; CD36 And LIMPII Analogous 1; CD36L1; CLA-1; SR-BI; CLA1; SRB1
- Gene ID
- 949
- UniProt ID
- Q8WTV0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone mAb15"
See other products for "SCARB1"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1865z | Mouse Anti-SCARB1 Recombinant Antibody (clone 4H1) | WB, ICC, IF, IHC | Mouse IgG1 |
| HPAB-0384-CN | Mouse Anti-SCARB1 Recombinant Antibody (HPAB-0384-CN) | ELISA, FC, IHC | Mouse IgG1 |
| HPAB-1609-FY | Recombinant Human Anti-SCARB1 Antibody (mAb8) | Inhib, Neut, FC | Human IgG4 |
| HPAB-1610-FY | Recombinant Human Anti-SCARB1 Antibody (mAb81) | Inhib, FC | Human IgG |
| VS3-WK1073 | Rabbit Anti-SCARB1 Recombinant Antibody (VS3-WK1073) | WB, ICC, IHC, FC | Rabbit IgG |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1927CQ | Recombinant Mouse Anti-Scarb1 Antibody (CBL917) | FC, IHC, Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3179 | Hi-Affi™ Recombinant Rabbit Anti-SCARB1 Monoclonal Antibody (DS3179AB) | WB, IHC, ICC | IgG |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0384-CN-S(P) | Mouse Anti-SCARB1 Recombinant Antibody; scFv Fragment (HPAB-0384-CN-S(P)) | ELISA, FC, IHC | Mouse scFv |
| HPAB-0298CQ-S(P) | Human Anti-SCARB1 Recombinant Antibody (clone scFVC11); scFv Fragment | ELISA, FuncS | Human scFv |
| HPAB-1609-FY-F(E) | Recombinant Human Anti-SCARB1 Antibody scFv Fragment (mAb8) | Inhib, ELISA, FC | Human scFv |
| HPAB-1610-FY-F(E) | Recombinant Human Anti-SCARB1 Antibody scFv Fragment (mAb81) | Inhib, ELISA | Human scFv |
| HPAB-1611-FY-F(E) | Recombinant Human Anti-SCARB1 Antibody scFv Fragment (mAb15) | Inhib, ELISA, FC | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0384-CN-F(E) | Mouse Anti-SCARB1 Recombinant Antibody; Fab Fragment (HPAB-0384-CN-F(E)) | ELISA, FC, IHC | Mouse Fab |
| HPAB-0298CQ-F(E) | Human Anti-SCARB1 Recombinant Antibody (clone scFVC11); Fab Fragment | ELISA, FuncS | Human Fab |
| HPAB-1609-FY-S(P) | Recombinant Human Anti-SCARB1 Antibody Fab Fragment (mAb8) | Inhib, ELISA, FC | Human Fab |
| HPAB-1610-FY-S(P) | Recombinant Human Anti-SCARB1 Antibody Fab Fragment (mAb81) | Inhib, ELISA | Human Fab |
| HPAB-1611-FY-S(P) | Recombinant Human Anti-SCARB1 Antibody Fab Fragment (mAb15) | Inhib, ELISA, FC | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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