Human Anti-SCARB1 Recombinant Antibody (clone scFVC11); Fab Fragment (CAT#: HPAB-0298CQ-F(E))
This product is a recombinant human antibody Fab fragment that recognizes SCARB1. The antibody binds to a SR-BI target region involved in HCV E2 binding. scFVC11 can block HCV infection of cultured human hepatocytes.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles & lysosomes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66285/1250_H7_5_selected.jpg
(Immunofluorescent staining of human cell line U-2 OS shows localization to vesicles & lysosomes.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/66285/1250_H7_5_selected.jpg
Figure 2 Adrenal gland
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70124/166148_B_4_5_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/70124/166148_B_4_5_val_selected.jpg
Figure 3 Kidney
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72449/166126_A_7_5.jpg
(Cells in glomeruli Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72449/166126_A_7_5.jpg
Figure 4 Testis
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72449/166126_A_4_6.jpg
(Leydig cells Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/72449/166126_A_4_6.jpg
Figure 5 RNA cell line category: Cell line enhanced (RPMI-8226)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000073060-SCARB1
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000073060-SCARB1
Specifications
- Immunogen
- Human SR-B1 receptor
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human SCARB1
- Species Reactivity
- Human
- Clone
- scFVC11
- Applications
- ELISA, FuncS
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Scavenger Receptor Class B Member 1; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Receptor)-Like 1; CD36 And LIMPII Analogous 1; CD36L1; CLA-1; SR-BI; CLA1; SRB1;
- Gene ID
- 949
- UniProt ID
- Q8WTV0
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1397CT | Recombinant Mouse anti-Rat SCARB1 Monoclonal antibody (4E23) | FC, IHC-Fr, Neut | |
| HPAB-0384-CN | Mouse Anti-SCARB1 Recombinant Antibody (HPAB-0384-CN) | ELISA, FC, IHC | Mouse IgG1 |
| VS3-FY1321 | Recombinant Rabbit Anti-SCARB1 Antibody (clone R06-6H2) | WB | Rabbit IgG |
| VS3-FY1322 | Recombinant Rabbit Anti-SCARB1 Antibody (clone R07-4H3) | WB, IP | Rabbit IgG |
| VS7-0425-WR830 | Mouse Anti-SCARB1 Recombinant Antibody (clone 5E9H10) | WB, IHC, FC | Mouse IgG2a |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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