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SERPINB9
This gene encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6.
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Langerhans cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (BEWO, SuSa, U-698)
Molecular function
Protease inhibitor, Serine protease inhibitor
More Types Infomation
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: IgG
- Application: WB, FC
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- Species Reactivity: Human
- Application: FC, WB
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For Research Use Only. Not For Clinical Use.