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SMC1B
SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001 [PubMed 11564881]).[supplied by OMIM, Mar 2008]
Predicted location
Intracellular
Single cell type specificity
Group enriched (Spermatocytes, Spermatogonia)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (A-431, EFO-21, SiHa, U-266/70)
Interaction
Forms a heterodimer with SMC3. Component of a meiosis-specific cohesin complex, probably composed of the SMC1B and SMC3 heterodimer attached via their SMC hinge domain, RAD21 (or its meiosis-specific related protein REC8), which link them, and STAG3, which interacts with RAD21 or REC8 (By similarity).
More Types Infomation
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- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.