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TREML1
This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants
Protein class
Plasma proteins
Predicted location
Membrane
Single cell type specificity
Group enriched (Macrophages, monocytes)
Immune cell specificity
Immune cell enriched (basophil)
Cell line specificity
Cell line enriched (HEL)
Interaction
When phosphorylated, interacts with PTPN6 (By similarity). When phosphorylated, interacts with PTPN11.
Molecular function
Receptor
More Types Infomation
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
- Recombinant Anti-Human TREML1 Antibody scFv Fragment (MOB-2642z-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FC, FuncS
- Recombinant Anti-Human TREML1 Antibody Fab Fragment (MOB-2642z-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, FuncS
-
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.