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TXNDC17
The biological function of TXNDC17 is not well understood, but it has been recently found that TXNDC17 is involved in the TNF (tumor necrosis factor) signaling pathway. A number of studies have demonstrated a role of TNF in stimulating autophagy in human cells, including macrophages, vascular smooth cells, skeletal muscle cells, T lymphoblastic leukemic cells, Ewing sarcoma cells, and breast cancer cells. Thus, there may be a link among TXNDC17 overexpression, autophagy, and paclitaxel resistance in ovarian cancer.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Proximal tubular cells, Basal respiratory cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Interacts with TRXR1 and DYNLL1/DNCL1.
More Types Infomation
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ELISA
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For Research Use Only. Not For Clinical Use.