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TYRP1
This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.
Protein class
Disease related genes, Human disease related genes, Metabolic proteins
Predicted location
Intracellular, Membrane (different isoforms)
Single cell type specificity
Cell type enriched (Melanocytes)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enriched (SK-MEL-30)
Interaction
Monomer (PubMed:28661582). Interacts with ATP7A (By similarity).
Molecular function
Monooxygenase, Oxidoreductase
More Types Infomation
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- Class: Class II
- Antigen: Tyrp1
- Antigen Species: Human
- Peptide: ISPNSVFSQWRVVCDSLEDYD
- Conjugate: BV421
-
- Class: Class II
- Antigen: Tyrp1
- Antigen Species: Human
- Peptide: ISPNSVFSQWRVVCDSLEDYD
-
- Class: Class II
- Antigen: Tyrp1
- Antigen Species: Human
- Peptide: ISPNSVFSQWRVVCDSLEDYD
- Conjugate: APC
-
- Class: Class II
- Antigen: Tyrp1
- Antigen Species: Human
- Peptide: ISPNSVFSQWRVVCDSLEDYD
- Conjugate: FITC
-
- Class: Class II
- Antigen: Tyrp1
- Antigen Species: Human
- Peptide: ISPNSVFSQWRVVCDSLEDYD
- Conjugate: Biotin
-
- Class: Class II
- Antigen: Tyrp1
- Antigen Species: Human
- Peptide: ISPNSVFSQWRVVCDSLEDYD
- Conjugate: PE
-
- Species Reactivity: Human
- Application: IHC-Fr, WB
- Recombinant Human Anti-human TYRP1 Antibody scFv Fragment (MHH-1020-S(P))
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- Derivation: Human
- Species Reactivity: Human
- Type: scFv
- Application: WB, IHC, FuncS
- Recombinant Anti-human TYRP1 Antibody scFv Fragment (MOB-1020-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
- Recombinant Anti-human TYRP1 Antibody Fab Fragment (MOB-1020-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: ELISA, FuncS
- Recombinant Anti-human TYRP1 Antibody (MOB-1020)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FC, FuncS
- Recombinant Human Anti-human TYRP1 Antibody (MHH-1020)
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, IF, FuncS
- Recombinant Human Anti-human TYRP1 Antibody Fab Fragment (MHH-1020-F(E))
-
- Derivation: Human
- Species Reactivity: Human
- Type: Fab
- Application: IF, FACS, FuncS
-
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC-P, IP
- Human Anti-TYRP1 Recombinant Antibody (clone TA99) (FAMAB-1756CQ)
-
- Species Reactivity: Human
- Type: Human IgG1
- Application: IP, WB, ELISA, FC, IF, IHC-Fr
- Rabbit Anti-TYRP1 Recombinant Antibody (clone JU36-48) (MRO-1533-CN)
-
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, IP
- Human Anti-TYRP1 Antibody (clone TA99), mRNA (FAMAB-1756CQ-mRNA)
-
- Species Reactivity: Human
- Recombinant Human Anti-TYRP1 Soluble TCR (scTCR-464CQ-S(P))
-
- Species Reactivity: Human
- Epitope: aa 277-297
- MHC: HLA-DR4
-
- Derivation: Human
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
- Mouse Anti-TYRP1 Recombinant Antibody (clone CTA99); scFv Fragment (HPAB-0123-LSX-S(P))
-
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
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For Research Use Only. Not For Clinical Use.