APC-DRB1*04:01/Human Tyrp1 (ISPNSVFSQWRVVCDSLEDYD) MHC Tetramer (CAT#: MHC-YF1005)
This product is a MHC tetramer of biotinylated peptide/MHC complex composed Tyrp1-derived peptide of ISPNSVFSQWRVVCDSLEDYD sequence covering 277-297 and DRB1*04:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.
Specific Inquiry
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line SK-MEL-30
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1291_B1_3_selected.jpg
(Immunofluorescent staining of human cell line SK-MEL-30 shows localization to vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1291_B1_3_selected.jpg
Figure 2 Skin
(Melanocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1995_B_9_1.jpg
(Melanocytes
Staining: High
Intensity: Strong
Quantity:>75%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/937/1995_B_9_1.jpg
Figure 3 RNA cell line category: Cell line enriched (SK-MEL-30)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000107165-TYRP1/subcellular
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000107165-TYRP1/subcellular
Specifications
- Allele
- DRB1*04:01
- Class
- Class II
- MHC Species
- Human
- Antigen
- Tyrp1
- Antigen Species
- Human
- Peptide
- ISPNSVFSQWRVVCDSLEDYD
- Range
- 277-297
- Conjugate
- APC
- Application
- FCM
Target
- Antigen Introduction
- This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.
- Alternative Names
- TRP; CAS2; CATB; GP75; OCA3; TRP1; TYRP; b-PROTEIN
- Gene ID
- 7306
- UniProt ID
- P17643
Downloads
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Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1020-F(E) | Recombinant Anti-human TYRP1 Antibody Fab Fragment | ELISA, FuncS | Fab |
| MHH-1020-F(E) | Recombinant Human Anti-human TYRP1 Antibody Fab Fragment | IF, FACS, FuncS | Fab |
| HPAB-0121-LSX-F(E) | Human Anti-TYRP1 Recombinant Antibody (clone 20D7); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0122-LSX-F(E) | Human Anti-TYRP1 Recombinant Antibody (clone 20D7S); Fab Fragment | ELISA, FC | Human Fab |
| HPAB-0123-LSX-F(E) | Human Anti-TYRP1 Recombinant Antibody (clone CTA99); Fab Fragment | ELISA, FC | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1020-S(P) | Recombinant Anti-human TYRP1 Antibody scFv Fragment | ELISA, WB, FuncS | scFv |
| MHH-1020-S(P) | Recombinant Human Anti-human TYRP1 Antibody scFv Fragment | WB, IHC, FuncS | scFv |
| HPAB-0121-LSX-S(P) | Human Anti-TYRP1 Recombinant Antibody (clone 20D7); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0122-LSX-S(P) | Human Anti-TYRP1 Recombinant Antibody (clone 20D7S); scFv Fragment | ELISA, FC | Human scFv |
| HPAB-0123-LSX-S(P) | Mouse Anti-TYRP1 Recombinant Antibody (clone CTA99); scFv Fragment | ELISA, FC | Mouse scFv |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-130 | Anti-Human TYRP1 Recombinant Antibody (Flanvotumab) | Neut, ELISA, IF, IP, FuncS, FC, ICC | IgG1 - kappa |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHH-1020 | Recombinant Human Anti-human TYRP1 Antibody | ELISA, IF, FuncS | IgG |
| MOB-2035CT | Recombinant Mouse anti-Human TYRP1 Monoclonal antibody (4G499) | IHC-Fr, WB | |
| HPAB-0121-LSX | Human Anti-TYRP1 Recombinant Antibody (clone 20D7) | ELISA, FC | Human IgG1, κ |
| HPAB-0122-LSX | Human Anti-TYRP1 Recombinant Antibody (clone 20D7S) | ELISA, FC | Human IgG1, κ |
| HPAB-0123-LSX | Human Anti-TYRP1 Recombinant Antibody (clone CTA99) | ELISA, FC | Human IgG |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3737 | Rabbit Anti-TYRP1 Recombinant Antibody (clone DS3737AB) | WB, IHC-P, IP | Rabbit IgG |
MHC Tetramer for Cancer
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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