APC-DRB1*04:01/Human Tyrp1 (ISPNSVFSQWRVVCDSLEDYD) MHC Tetramer

CAT#: MHC-YF1005

This product is a MHC tetramer of biotinylated peptide/MHC complex composed Tyrp1-derived peptide of ISPNSVFSQWRVVCDSLEDYD sequence covering 277-297 and DRB1*04:01 molecule. The pMHC tetramer recognizes CD8 T cells and can be used in the MHC tetramer analysis of individual antigen-specific T cells.

Gene Expression
Figure 1 IF staining of human cell line SK-MEL-30 Figure 2 Skin Figure 3 RNA cell line category: Cell line enriched (SK-MEL-30)

Specifications

  • Allele
  • DRB1*04:01
  • Class
  • Class II
  • MHC Species
  • Human
  • Antigen
  • Tyrp1
  • Antigen Species
  • Human
  • Peptide
  • ISPNSVFSQWRVVCDSLEDYD
  • Range
  • 277-297
  • Conjugate
  • APC
  • Application
  • FCM

Target

  • Antigen Introduction
  • This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III.
  • Alternative Names
  • TRP; CAS2; CATB; GP75; OCA3; TRP1; TYRP; b-PROTEIN
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